Active: Acute lymphoblastic leukemia (childhood) Clear all

GWAS 2023-09-13

Evaluating Genomic Polygenic Risk Scores for Childhood Acute Lymphoblastic Leukemia in Latinos.

Jeon S, Lo YC et al.

HGG Adv

The utility of polygenic risk score (PRS) models has not been comprehensively evaluated for childhoo...

Acute lymphoblastic leukemia (childhood)

77632

Participants

N/A

Studies

Details PubMed

GWAS 2018-01-18

GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.

Wiemels JL, Walsh KM et al.

Nat Commun

Childhood acute lymphoblastic leukemia (ALL) (age 0-14 years) is 20% more common in Latino Americans...

Acute lymphoblastic leukemia (childhood)

Replicated

23864

Participants

N/A

Studies

Details PubMed

GWAS 2017-08-17

Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility.

Archer NP, Perez-Andreu V et al.

PLoS One

We conducted an exome-wide association study of childhood acute lymphoblastic leukemia (ALL) among H...

Acute lymphoblastic leukemia (childhood)

299

Participants

N/A

Studies

Details PubMed

GWAS 2014-10-13

Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures.

Evans TJ, Milne E et al.

PLoS One

Genome wide association studies (GWAS) have established association of ARID5B and IKZF1 variants wit...

Acute lymphoblastic leukemia (childhood)

Replicated

3533

Participants

N/A

Studies

Details PubMed

GWAS 2013-10-20

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse.

Perez-Andreu V, Roberts KG et al.

Nat Genet

Recent genomic profiling of childhood acute lymphoblastic leukemia (ALL) identified a high-risk subt...

Acute lymphoblastic leukemia (childhood)

Replicated

13163

Participants

N/A

Studies

Details PubMed

GWAS 2013-03-19

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.

Xu H, Yang W et al.

J Natl Cancer Inst

Acute lymphoblastic leukemia (ALL) is the most common cancer in children and the incidence of ALL va...

Acute lymphoblastic leukemia (childhood)

Replicated

10284

Participants

N/A

Studies

Details PubMed

GWAS 2012-09-24

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia.

Yang JJ, Cheng C et al.

Blood

With the use of risk-directed therapy for childhood acute lymphoblastic leukemia (ALL), outcome has ...

Acute lymphoblastic leukemia (childhood)

Replicated

2535

Participants

N/A

Studies

Details PubMed

GWAS 2011-11-11

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

Ellinghaus E, Stanulla M et al.

Leukemia

Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...

Acute lymphoblastic leukemia (childhood)

Replicated

5231

Participants

N/A

Studies

Details PubMed

GWAS 2010-08-01

Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma.

Horinouchi M, Yagi M et al.

Pediatr Hematol Oncol

The objective of this study was to identify novel pharmacogenetic determinants of treatment-related ...

Acute lymphoblastic leukemia (childhood)

Replicated

Participants

N/A

Studies

Details PubMed

GWAS 2010-02-25

Genome-wide association study of childhood acute lymphoblastic leukemia in Korea.

Han S, Lee KM et al.

Leuk Res

We conducted a genome-wide association study of childhood acute lymphoblastic leukemia (ALL) in a ca...

Acute lymphoblastic leukemia (childhood)

Participants

N/A

Studies

Details PubMed

GWAS 2009-08-16

Germline genomic variants associated with childhood acute lymphoblastic leukemia.

Treviño LR, Yang W et al.

Nat Genet

Using the Affymetrix 500K Mapping array and publicly available genotypes, we identified 18 SNPs whos...

Acute lymphoblastic leukemia (childhood)

19275

Participants

N/A

Studies

Details PubMed

GWAS 2009-08-16

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.

Papaemmanuil E, Hosking FJ et al.

Nat Genet

To identify risk variants for childhood acute lymphoblastic leukemia (ALL), we conducted a genome-wi...

Acute lymphoblastic leukemia (childhood)

3305

Participants

N/A

Studies

Details PubMed

Title

Author

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Disease/Trait

Date

Actions

Evaluating Genomic Polygenic Risk Scores for Childhood Acute Lymphoblastic Leukemia in Latinos.

Jeon S, Lo YC et al.

HGG Adv

Acute lymphoblastic leukemia (childhood)

2023-09-13

GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.

Wiemels JL, Walsh KM et al.

Nat Commun

Acute lymphoblastic leukemia (childhood)

2018-01-18

Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility.

Archer NP, Perez-Andreu V et al.

PLoS One

Acute lymphoblastic leukemia (childhood)

2017-08-17

Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures.

Evans TJ, Milne E et al.

PLoS One

Acute lymphoblastic leukemia (childhood)

2014-10-13

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse.

Perez-Andreu V, Roberts KG et al.

Nat Genet

Acute lymphoblastic leukemia (childhood)

2013-10-20

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.

Xu H, Yang W et al.

J Natl Cancer Inst

Acute lymphoblastic leukemia (childhood)

2013-03-19

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia.

Yang JJ, Cheng C et al.

Blood

Acute lymphoblastic leukemia (childhood)

2012-09-24

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

Ellinghaus E, Stanulla M et al.

Leukemia

Acute lymphoblastic leukemia (childhood)

2011-11-11

Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma.

Horinouchi M, Yagi M et al.

Pediatr Hematol Oncol

Acute lymphoblastic leukemia (childhood)

2010-08-01

Genome-wide association study of childhood acute lymphoblastic leukemia in Korea.

Han S, Lee KM et al.

Leuk Res

Acute lymphoblastic leukemia (childhood)

2010-02-25

Germline genomic variants associated with childhood acute lymphoblastic leukemia.

Treviño LR, Yang W et al.

Nat Genet

Acute lymphoblastic leukemia (childhood)

2009-08-16

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.

Papaemmanuil E, Hosking FJ et al.

Nat Genet

Acute lymphoblastic leukemia (childhood)

2009-08-16