Active: Alcohol dependence Clear all

GWAS 2023-06-21

Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders.

Saenz de Viteri S, Zhang J et al.

Mol Psychiatry

Recent genome-wide association studies (GWAS) have identified genetic markers of post-traumatic stre...

Post-traumatic stress disorder

4978

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-22

A Genome-Wide Association Study Reveals a <i>BDNF</i>-Centered Molecular Network Associated with Alcohol Dependence and Related Clinical Measures.

Levchenko A, Malov S et al.

Biomedicines

At least 50% of factors predisposing to alcohol dependence (AD) are genetic and women affected with ...

Alcohol dependence (codominant genetic model)

1208

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-29

Genome-wide meta-analysis of alcohol use disorder in East Asians.

Zhou H, Kalayasiri R et al.

Neuropsychopharmacology

Alcohol use disorder (AUD) is a leading cause of death and disability worldwide. Genome-wide associa...

Alcohol use disorder

13551

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-02

Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry.

Sanchez-Roige S, Fontanillas P et al.

Mol Psychiatry

The growing prevalence of opioid use disorder (OUD) constitutes an urgent health crisis. Ample evide...

Problematic opioid prescription use

132113

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-29

Genome-wide association study of stimulant dependence.

Cox J, Sherva R et al.

Transl Psychiatry

Stimulant dependence is heritable, but specific genetic factors underlying the trait have not been i...

Stimulant dependence

Replicated

22416

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-07

The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses.

Li W, Thygesen JH et al.

Psychiatr Genet

Introduction: Genome-wide association studies (GWAS) of alcohol dependence syndrome (ADS) offer a pl...

Alcohol dependence

1990

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-01

A Family-Based Genome Wide Association Study of Externalizing Behaviors.

Barr PB, Salvatore JE et al.

Behav Genet

Shared genetic factors contribute to the high degree of comorbidity among externalizing problems (e....

Externalizing behaviour score

15112

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-07

Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison.

Sun Y, Chang S et al.

Transl Psychiatry

Alcohol-related behaviors are moderately heritable and have ethnic-specific characteristics. At pres...

Alcohol dependence

Replicated

3727

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-28

Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence.

Sun Y, Chang S et al.

Mol Psychiatry

Different substance dependences have common effects on reward pathway and molecular adaptations, how...

Alcohol dependence or heroin dependence or methamphetamine dependence

Replicated

10013

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-03

Genome-wide association studies of the self-rating of effects of ethanol (SRE).

Lai D, Wetherill L et al.

Addict Biol

The level of response (LR) to alcohol as measured with the Self-Report of the Effects of Alcohol Ret...

Number of alcoholic drinks required to feel an effect (first five times drinking)

Replicated

6725

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-17

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans.

Wetherill L, Lai D et al.

Genes Brain Behav

Genetic influences on alcohol and drug dependence partially overlap, however, specific loci underlyi...

Alcohol or illicit drug dependence

Replicated

14885

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-14

Genome-wide association studies of alcohol dependence, DSM-IV criterion count, and individual criteria.

Lai D, Wetherill L et al.

Genes Brain Behav

Genome-wide association studies (GWAS) of alcohol dependence (AD) have reliably identified variation...

Alcohol dependence

Replicated

13650

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders.

Saenz de Viteri S, Zhang J et al.

Mol Psychiatry

Post-traumatic stress disorder

2023-06-21

A Genome-Wide Association Study Reveals a <i>BDNF</i>-Centered Molecular Network Associated with Alcohol Dependence and Related Clinical Measures.

Levchenko A, Malov S et al.

Biomedicines

Alcohol dependence (codominant genetic model)

2022-11-22

Genome-wide meta-analysis of alcohol use disorder in East Asians.

Zhou H, Kalayasiri R et al.

Neuropsychopharmacology

Alcohol use disorder

2022-01-29

Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry.

Sanchez-Roige S, Fontanillas P et al.

Mol Psychiatry

Problematic opioid prescription use

2021-11-02

Genome-wide association study of stimulant dependence.

Cox J, Sherva R et al.

Transl Psychiatry

Stimulant dependence

2021-06-29

The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses.

Li W, Thygesen JH et al.

Psychiatr Genet

Alcohol dependence

2020-12-07

A Family-Based Genome Wide Association Study of Externalizing Behaviors.

Barr PB, Salvatore JE et al.

Behav Genet

Externalizing behaviour score

2020-04-01

Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison.

Sun Y, Chang S et al.

Transl Psychiatry

Alcohol dependence

2019-10-07

Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence.

Sun Y, Chang S et al.

Mol Psychiatry

Alcohol dependence or heroin dependence or methamphetamine dependence

2019-08-28

Genome-wide association studies of the self-rating of effects of ethanol (SRE).

Lai D, Wetherill L et al.

Addict Biol

Number of alcoholic drinks required to feel an effect (first five times drinking)

2019-07-03

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans.

Wetherill L, Lai D et al.

Genes Brain Behav

Alcohol or illicit drug dependence

2019-05-17

Genome-wide association studies of alcohol dependence, DSM-IV criterion count, and individual criteria.

Lai D, Wetherill L et al.

Genes Brain Behav

Alcohol dependence

2019-05-14