Active: Behcet's disease Clear all

GWAS 2023-11-15

Genome-wide association analysis reveals the associations of NPHP4, TYW1-AUTS2 and SEMA6D for Behçet's disease and HLA-B*46:01 for its intestinal involvement.

Jung ES, Ellinghaus D et al.

Dig Liver Dis

Intestinal involvement in Behçet's disease (BD) is associated with poor prognosis and is more preval...

Behcet's disease

Replicated

5346

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-02

Clinical trait-specific genetic analysis in Behçet's disease identifies novel loci associated with ocular and neurological involvement.

Casares-Marfil D, Esencan D et al.

Clin Immunol

Behçet's disease is a complex inflammatory vasculitis with a broad spectrum of clinical manifestatio...

Genital aphthosis in Behcet's disease

435

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-04

Genetic association of a gain of function interferon gamma receptor 1 (IFNGR1) polymorphism and the intergenic region LNCAROD/DKK1 with Behçet's disease.

Ortiz Fernández L, Coit P et al.

Arthritis Rheumatol

Objective: Behçet's disease is a complex systemic inflammatory vasculitis of incompletely understood...

Behcet's disease

8982

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-03

Identification of genetic susceptibility loci for intestinal Behçet's disease.

Kim SW, Jung YS et al.

Sci Rep

Several recent genome-wide association studies (GWAS) identified susceptibility loci/genes for Behçe...

Behcet's disease

Replicated

1521

Participants

N/A

Studies

Details PubMed

GWAS 2016-08-22

Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.

Ortiz-Fernández L, Carmona FD et al.

PLoS One

Behcet's disease (BD) is an immuno-mediated vasculitis in which knowledge of its etiology and geneti...

Behcet's disease

Replicated

2530

Participants

N/A

Studies

Details PubMed

GWAS 2015-03-23

Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease.

Kappen JH, Medina-Gomez C et al.

PLoS One

Introduction: The etiology of Behçet's disease (BD) is unknown, but widely considered an excessive T...

Behcet's disease

Replicated

6359

Participants

N/A

Studies

Details PubMed

GWAS 2013-12-10

FUT2: filling the gap between genes and environment in Behçet's disease?

Xavier JM, Shahram F et al.

Ann Rheum Dis

Objectives: To identify new susceptibility loci for Behçet's disease (BD), we performed a genome-wid...

Behcet's disease

Replicated

4295

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-06

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.

Kirino Y, Bertsias G et al.

Nat Genet

Individuals with Behçet's disease suffer from episodic inflammation often affecting the orogenital m...

Behcet's disease

Replicated

5313

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-06

Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.

Hou S, Yang Z et al.

Arthritis Rheum

Objective: To identify susceptibility loci for Behçet's disease (BD) and elucidate their functional ...

Behcet's disease

Replicated

2811

Participants

N/A

Studies

Details PubMed

GWAS 2012-10-06

Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.

Lee YJ, Horie Y et al.

Ann Rheum Dis

Objectives: To identify non-major histocompatibility complex susceptible genes that might contribute...

Behcet's disease

Replicated

1802

Participants

N/A

Studies

Details PubMed

GWAS 2010-07-11

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.

Remmers EF, Cosan F et al.

Nat Genet

Behçet's disease is a genetically complex disease of unknown etiology characterized by recurrent inf...

Behcet's disease

Replicated

5090

Participants

N/A

Studies

Details PubMed

GWAS 2010-07-11

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci.

Mizuki N, Meguro A et al.

Nat Genet

Behçet's disease is a chronic systemic inflammatory disorder characterized by four major manifestati...

Behcet's disease

Replicated

4101

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association analysis reveals the associations of NPHP4, TYW1-AUTS2 and SEMA6D for Behçet's disease and HLA-B*46:01 for its intestinal involvement.

Jung ES, Ellinghaus D et al.

Dig Liver Dis

Behcet's disease

2023-11-15

Clinical trait-specific genetic analysis in Behçet's disease identifies novel loci associated with ocular and neurological involvement.

Casares-Marfil D, Esencan D et al.

Clin Immunol

Genital aphthosis in Behcet's disease

2023-06-02

Genetic association of a gain of function interferon gamma receptor 1 (IFNGR1) polymorphism and the intergenic region LNCAROD/DKK1 with Behçet's disease.

Ortiz Fernández L, Coit P et al.

Arthritis Rheumatol

Behcet's disease

2021-01-04

Identification of genetic susceptibility loci for intestinal Behçet's disease.

Kim SW, Jung YS et al.

Sci Rep

Behcet's disease

2017-01-03

Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.

Ortiz-Fernández L, Carmona FD et al.

PLoS One

Behcet's disease

2016-08-22

Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease.

Kappen JH, Medina-Gomez C et al.

PLoS One

Behcet's disease

2015-03-23

FUT2: filling the gap between genes and environment in Behçet's disease?

Xavier JM, Shahram F et al.

Ann Rheum Dis

Behcet's disease

2013-12-10

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.

Kirino Y, Bertsias G et al.

Nat Genet

Behcet's disease

2013-01-06

Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.

Hou S, Yang Z et al.

Arthritis Rheum

Behcet's disease

2012-12-06

Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.

Lee YJ, Horie Y et al.

Ann Rheum Dis

Behcet's disease

2012-10-06

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.

Remmers EF, Cosan F et al.

Nat Genet

Behcet's disease

2010-07-11

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci.

Mizuki N, Meguro A et al.

Nat Genet

Behcet's disease

2010-07-11