Active: Cerebrovascular disease Clear all

GWAS 2023-12-01

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.

Liu M, Khasiyev F et al.

J Am Heart Assoc

Brain arterial diameters (BADs) are novel imaging biomarkers of cerebrovascular disease, cognitive d...

Global brain arterial diameters

4150

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-24

Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese.

Shih CH, Chuang HK et al.

Front Genet

Age-related macular degeneration (AMD) is the main cause of severe vision loss in elderly population...

Age-related macular degeneration

3729

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-22

Identifying genetic variants associated with the ICD10 (International Classification of Diseases10)-based diagnosis of cerebrovascular disease using a large-scale biomedical database.

Alkhalfan F, Gyftopoulos A et al.

PLoS One

Objectives: To utilize the UK Biobank to identify genetic variants associated with the ICD10 (Intern...

Cerebrovascular disease

131796

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-03

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

Francis CM, Futschik ME et al.

Nat Commun

Aortic dimensions and distensibility are key risk factors for aortic aneurysms and dissections, as w...

Ascending aorta maximum area

Replicated

32590

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-06

Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.

Lee SB, Choi JE et al.

Biomedicines

A comprehensive understanding of gene-diet interactions is necessary to establish proper dietary gui...

Total cholesterol levels

58701

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-08

Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease.

Yu M, Tcheandjieu C et al.

JCI Insight

The fibrous annulus of the mitral valve plays an important role in valvular function and cardiac phy...

Mitral valve annular diameter (left ventricle systole)

27156

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-23

Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer's pathophysiology.

Ramanan VK, Lesnick TG et al.

Acta Neuropathol Commun

Although abnormal accumulation of amyloid in the brain is an early biomarker of Alzheimer's disease ...

Cognitive resilience in amyloidosis

Replicated

1091

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-25

Identification of susceptibility loci for cardiovascular disease in adults with hypertension, diabetes, and dyslipidemia.

Song Y, Choi JE et al.

J Transl Med

Hypertension (HTN), diabetes mellitus (DM), and dyslipidemia (DL) are well-known risk factors of car...

Cardio-cerebrovascular disease in hypertension

16302

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-15

Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response.

Marshe VS, Maciukiewicz M et al.

Transl Psychiatry

Antidepressant outcomes in older adults with depression is poor, possibly because of comorbidities s...

Remission after antidepressant treatment in major depression

Replicated

1381

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-26

Variants in PPP2R2B and IGF2BP3 are associated with higher tau deposition.

Ramanan VK, Wang X et al.

Brain Commun

Tau deposition is a key biological feature of Alzheimer's disease that is closely related to cogniti...

Tau burden

754

Participants

N/A

Studies

Details PubMed

GWAS 2015-12-30

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.

Williams SR, Hsu FC et al.

Neurology

Objective: To investigate the genetic contributors to cerebrovascular disease and variation in bioma...

C-reactive protein levels in ischemic stroke

2100

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.

Liu M, Khasiyev F et al.

J Am Heart Assoc

Global brain arterial diameters

2023-12-01

Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese.

Shih CH, Chuang HK et al.

Front Genet

Age-related macular degeneration

2023-02-24

Identifying genetic variants associated with the ICD10 (International Classification of Diseases10)-based diagnosis of cerebrovascular disease using a large-scale biomedical database.

Alkhalfan F, Gyftopoulos A et al.

PLoS One

Cerebrovascular disease

2022-08-22

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

Francis CM, Futschik ME et al.

Nat Commun

Ascending aorta maximum area

2022-08-03

Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.

Lee SB, Choi JE et al.

Biomedicines

Total cholesterol levels

2022-07-06

Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease.

Yu M, Tcheandjieu C et al.

JCI Insight

Mitral valve annular diameter (left ventricle systole)

2022-02-08

Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer's pathophysiology.

Ramanan VK, Lesnick TG et al.

Acta Neuropathol Commun

Cognitive resilience in amyloidosis

2021-03-23

Identification of susceptibility loci for cardiovascular disease in adults with hypertension, diabetes, and dyslipidemia.

Song Y, Choi JE et al.

J Transl Med

Cardio-cerebrovascular disease in hypertension

2021-02-25

Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response.

Marshe VS, Maciukiewicz M et al.

Transl Psychiatry

Remission after antidepressant treatment in major depression

2021-02-15

Variants in PPP2R2B and IGF2BP3 are associated with higher tau deposition.

Ramanan VK, Wang X et al.

Brain Commun

Tau burden

2020-09-26

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.

Williams SR, Hsu FC et al.

Neurology

C-reactive protein levels in ischemic stroke

2015-12-30

Health & Traits Publications

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.

Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese.

Identifying genetic variants associated with the ICD10 (International Classification of Diseases10)-based diagnosis of cerebrovascular disease using a large-scale biomedical database.

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.

Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease.

Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer's pathophysiology.

Identification of susceptibility loci for cardiovascular disease in adults with hypertension, diabetes, and dyslipidemia.

Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response.

Variants in <i>PPP2R2B</i> and <i>IGF2BP3</i> are associated with higher tau deposition.

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.