Active: Cortical surface area Clear all

GWAS 2025-11-11

A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders.

Smeland OB, Kutrolli G et al.

Nat Neurosci

Although neurological and psychiatric disorders have historically been considered to reflect distinc...

Total cortical surface area

32877

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-03

Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases.

Makowski C, van der Meer D et al.

Science

To determine the impact of genetic variants on the brain, we used genetically informed brain atlases...

Dorsomedial frontal area

Replicated

49034

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-21

Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

Shadrin AA, Kaufmann T et al.

Neuroimage

Brain morphology has been shown to be highly heritable, yet only a small portion of the heritability...

Cortical surface area

35657

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-22

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.

Hofer E, Roshchupkin GV et al.

Nat Commun

Cortical thickness, surface area and volumes vary with age and cognitive function, and in neurologic...

Cortical surface area

Replicated

40980

Participants

N/A

Studies

Details PubMed

GWAS 2020-03-20

Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes.

Shin J, Ma S et al.

Cereb Cortex

We have carried out meta-analyses of genome-wide association studies (GWAS) (n = 23 784) of the firs...

Cortical surface area (visual PC2)

Replicated

49530

Participants

N/A

Studies

Details PubMed

GWAS 2020-02-11

Genetic control of variability in subcortical and intracranial volumes.

Córdova-Palomera A, van der Meer D et al.

Mol Psychiatry

Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at th...

Brain imaging measurements (variance)

25575

Participants

N/A

Studies

Details PubMed

GWAS 2014-08-29

A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.

Cai DC, Fonteijn H et al.

Genes Brain Behav

Heschl's gyrus (HG) is a core region of the auditory cortex whose morphology is highly variable acro...

Heschl's gyrus morphology

3054

Participants

N/A

Studies

Details PubMed

GWAS 2012-02-16

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.

Bakken TE, Roddey JC et al.

Proc Natl Acad Sci U S A

Visual cortical surface area varies two- to threefold between human individuals, is highly heritable...

Occipital cortical area (total cortical area interaction)

Replicated

1181

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders.

Smeland OB, Kutrolli G et al.

Nat Neurosci

Total cortical surface area

2025-11-11

Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases.

Makowski C, van der Meer D et al.

Science

Dorsomedial frontal area

2022-02-03

Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

Shadrin AA, Kaufmann T et al.

Neuroimage

Cortical surface area

2021-09-21

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.

Hofer E, Roshchupkin GV et al.

Nat Commun

Cortical surface area

2020-09-22

Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes.

Shin J, Ma S et al.

Cereb Cortex

Cortical surface area (visual PC2)

2020-03-20

Genetic control of variability in subcortical and intracranial volumes.

Córdova-Palomera A, van der Meer D et al.

Mol Psychiatry

Brain imaging measurements (variance)

2020-02-11

A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.

Cai DC, Fonteijn H et al.

Genes Brain Behav

Heschl's gyrus morphology

2014-08-29

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.

Bakken TE, Roddey JC et al.

Proc Natl Acad Sci U S A

Occipital cortical area (total cortical area interaction)

2012-02-16