Active: Cytokine levels Clear all

GWAS 2025-01-10

The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases.

Konieczny MJ, Omarov M et al.

Commun Biol

Circulating cytokines orchestrate immune reactions and are promising drug targets for immune-mediate...

CCL2 protein levels

74783

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-23

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth.

Wang Y, Nudel R et al.

PLoS Genet

Circulating inflammatory markers are essential to human health and disease, and they are often dysre...

C-reactive protein levels

Replicated

8318

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-30

Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.

Nath AP, Ritchie SC et al.

Am J Hum Genet

Cytokines are essential regulatory components of the immune system, and their aberrant levels have b...

Cytokine levels

9263

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-04

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis.

Li Z, Akar S et al.

PLoS Genet

Ankylosing spondylitis (AS) is a highly heritable immune-mediated arthritis common in Turkish and Ir...

Ankylosing spondylitis

3004

Participants

N/A

Studies

Details PubMed

GWAS 2013-10-29

Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults.

Matteini AM, Li J et al.

Cytokine

Activation of inflammatory pathways measured by serum inflammatory markers such as interleukin-18 (I...

Inflammatory biomarkers

4443

Participants

N/A

Studies

Details PubMed

GWAS 2013-06-18

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort.

Larsen MH, Albrechtsen A et al.

PLoS One

Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflam...

Lipopolysaccharide induced cytokine levels

Replicated

716

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases.

Konieczny MJ, Omarov M et al.

Commun Biol

CCL2 protein levels

2025-01-10

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth.

Wang Y, Nudel R et al.

PLoS Genet

C-reactive protein levels

2020-11-23

Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.

Nath AP, Ritchie SC et al.

Am J Hum Genet

Cytokine levels

2019-10-30

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis.

Li Z, Akar S et al.

PLoS Genet

Ankylosing spondylitis

2019-04-04

Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults.

Matteini AM, Li J et al.

Cytokine

Inflammatory biomarkers

2013-10-29

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort.

Larsen MH, Albrechtsen A et al.

PLoS One

Lipopolysaccharide induced cytokine levels

2013-06-18