Active: Dermatomyositis Clear all

GWAS 2022-01-31

Association with HLA-DRβ1 position 37 distinguishes juvenile Dermatomyositis from adult-onset myositis.

Deakin CT, Bowes J et al.

Hum Mol Genet

Juvenile dermatomyositis (JDM) is a rare, severe autoimmune disease and the most common idiopathic i...

Juvenile dermatomyositis

13064

Participants

N/A

Studies

Details PubMed

GWAS 2018-01-13

Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis.

Kochi Y, Kamatani Y et al.

Ann Rheum Dis

Objectives: Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare autoimmune d...

Idiopathic inflammatory myopathy

Replicated

6846

Participants

N/A

Studies

Details PubMed

GWAS 2016-05-06

Variation at HLA-DPB1 is associated with dermatomyositis in Chinese population.

Zhang CE, Li Y et al.

J Dermatol

Dermatomyositis (DM) is a polygenic disorder characterized by inflammation of skeletal muscle and sk...

Dermatomyositis

1693

Participants

N/A

Studies

Details PubMed

GWAS 2015-09-11

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.

Rothwell S, Cooper RG et al.

Ann Rheum Dis

Objectives: The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare autoimmu...

Dermatomyositis or juvenile dermatomyositis

16530

Participants

N/A

Studies

Details PubMed

GWAS 2015-08-20

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.

Miller FW, Chen W et al.

Genes Immun

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic a...

Myositis

6434

Participants

N/A

Studies

Details PubMed

GWAS 2013-08-27

Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders.

Miller FW, Cooper RG et al.

Arthritis Rheum

Objective: To identify new genetic associations with juvenile and adult dermatomyositis (DM).

Dermatomyositis

5902

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Association with HLA-DRβ1 position 37 distinguishes juvenile Dermatomyositis from adult-onset myositis.

Deakin CT, Bowes J et al.

Hum Mol Genet

Juvenile dermatomyositis

2022-01-31

Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis.

Kochi Y, Kamatani Y et al.

Ann Rheum Dis

Idiopathic inflammatory myopathy

2018-01-13

Variation at HLA-DPB1 is associated with dermatomyositis in Chinese population.

Zhang CE, Li Y et al.

J Dermatol

Dermatomyositis

2016-05-06

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.

Rothwell S, Cooper RG et al.

Ann Rheum Dis

Dermatomyositis or juvenile dermatomyositis

2015-09-11

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.

Miller FW, Chen W et al.

Genes Immun

Myositis

2015-08-20

Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders.

Miller FW, Cooper RG et al.

Arthritis Rheum

Dermatomyositis

2013-08-27