Active: Esophageal cancer Clear all

GWAS 2024-01-26

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people.

Koyanagi YN, Nakatochi M et al.

Sci Adv

An East Asian-specific variant on aldehyde dehydrogenase 2 (ALDH2 rs671, G>A) is the major geneti...

Daily alcohol intake in rs671 GG genotype

87980

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-26

GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L et al.

Gut

Objective: Oesophageal cancer (EC) is the sixth leading cause of cancer-related deaths. Oesophageal ...

Barrett's esophagus or Esophageal adenocarcinoma

49266

Participants

N/A

Studies

Details PubMed

GWAS 2012-09-09

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.

Wu C, Kraft P et al.

Nat Genet

We conducted a genome-wide association study (GWAS) and a genome-wide gene-environment interaction a...

Esophageal cancer (squamous cell)

Replicated

20787

Participants

N/A

Studies

Details PubMed

GWAS 2011-06-05

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

Wu C, Hu Z et al.

Nat Genet

Esophageal squamous-cell carcinoma (ESCC) is one of the most prevalent cancers worldwide and occurs ...

Esophageal cancer

Replicated

12218

Participants

N/A

Studies

Details PubMed

GWAS 2010-08-22

A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma.

Abnet CC, Freedman ND et al.

Nat Genet

We conducted a genome-wide association study of gastric cancer and esophageal squamous cell carcinom...

Esophageal cancer and gastric cancer

5623

Participants

N/A

Studies

Details PubMed

GWAS 2010-08-22

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.

Wang LD, Zhou FY et al.

Nat Genet

We performed a genome-wide association study of esophageal squamous cell carcinoma (ESCC) by genotyp...

Esophageal cancer

Replicated

22336

Participants

N/A

Studies

Details PubMed

GWAS 2009-08-18

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.

Cui R, Kamatani Y et al.

Gastroenterology

Background & aims: Esophageal squamous cell carcinoma (ESCC) is prevalent among Asian population...

Esophageal cancer

Replicated

3789

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people.

Koyanagi YN, Nakatochi M et al.

Sci Adv

Daily alcohol intake in rs671 GG genotype

2024-01-26

GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L et al.

Gut

Barrett's esophagus or Esophageal adenocarcinoma

2022-07-26

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.

Wu C, Kraft P et al.

Nat Genet

Esophageal cancer (squamous cell)

2012-09-09

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

Wu C, Hu Z et al.

Nat Genet

Esophageal cancer

2011-06-05

A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma.

Abnet CC, Freedman ND et al.

Nat Genet

Esophageal cancer and gastric cancer

2010-08-22

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.

Wang LD, Zhou FY et al.

Nat Genet

Esophageal cancer

2010-08-22

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.

Cui R, Kamatani Y et al.

Gastroenterology

Esophageal cancer

2009-08-18