Active: Estimated glomerular filtration rate Clear all

GWAS 2025-10-10

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.

Monteiro-Martins S, Li Y et al.

Kidney Int

Introduction: Chronic kidney disease (CKD) is defined as sustained abnormalities in kidney function ...

Kidney volume

38816

Participants

N/A

Studies

Details PubMed

GWAS 2025-02-10

Genetic analysis of elevated levels of creatinine and cystatin C biomarkers reveals novel genetic loci associated with kidney function.

D'Antonio M, Arthur TD et al.

Hum Mol Genet

The rising prevalence of chronic kidney disease (CKD), affecting an estimated 37 million adults in t...

Estimated glomerular filtration rate based on creatinine (2009 formula) in top 10% of individuals by creatinine levels

40170

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-02

Genome-wide characterization of 54 urinary metabolites reveals molecular impact of kidney function.

Valo E, Richmond A et al.

Nat Commun

Dissecting the genetic mechanisms underlying urinary metabolite concentrations can provide molecular...

Urinary acetate to urinary creatinine ratio

7998

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-10

Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function.

Loeb GB, Kathail P et al.

Nat Genet

Kidney failure, the decrease of kidney function below a threshold necessary to support life, is a ma...

Estimated glomerular filtration rate (creatinine, cystatin c)

406504

Participants

N/A

Studies

Details PubMed

GWAS 2024-07-11

Gene-vegetarianism interactions in calcium, estimated glomerular filtration rate, and testosterone identified in genome-wide analysis across 30 biomarkers.

Francis M, Westerman KE et al.

PLoS Genet

We examined the associations of vegetarianism with metabolic biomarkers using traditional and geneti...

Sex hormone binding globulin levels (adjusted for BMI) x vegetarianism interaction

133007

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-18

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.

Scholz M, Horn K et al.

Nat Commun

X-chromosomal genetic variants are understudied but can yield valuable insights into sexually dimorp...

Blood urea nitrogen levels

180748

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-20

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.

Hughes O, Bentley AR et al.

Cell Genom

Chronic kidney disease is a leading cause of death and disability globally and impacts individuals o...

Estimated glomerular filtration rate

145732

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-03

Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants.

Lee DJ, Moon JS et al.

Kidney Res Clin Pract

Chronic kidney disease is a significant health burden worldwide, with increasing incidence. Although...

Estimated glomerular filtration rate

58406

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-18

Association of biological age with health outcomes and its modifiable factors.

Liu WS, You J et al.

Aging Cell

Identifying the clinical implications and modifiable and unmodifiable factors of aging requires the ...

Biological age gap

9008

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-12

Genome-Wide Association Studies for Albuminuria of non-Diabetic Taiwanese Population.

Yang WS, Chuang GT et al.

Am J Nephrol

Introduction: Chronic kidney disease, which is defined by a reduced estimated glomerular filtration ...

Albuminuria

6768

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-01

Genome-Wide Association Study of Chronic Kidney Disease Progression.

Robinson-Cohen C, Triozzi JL et al.

J Am Soc Nephrol

Significance statement: Rapid progression of CKD is associated with poor clinical outcomes. Most pre...

Estimated glomerular filtration rate

116960

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-10

Identification of Genetic Markers Linked to The Activity of Indoleamine 2,3-Dioxygenase and Kidney Function.

Kim HR, Jin HS et al.

Metabolites

Indoleamine 2,3-dioxygenase (IDO) is a tryptophan-degrading enzyme belonging to the kynurenine pathw...

Indoleamine 2,3-dioxygenase activity

2579

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.

Monteiro-Martins S, Li Y et al.

Kidney Int

Kidney volume

2025-10-10

Genetic analysis of elevated levels of creatinine and cystatin C biomarkers reveals novel genetic loci associated with kidney function.

D'Antonio M, Arthur TD et al.

Hum Mol Genet

Estimated glomerular filtration rate based on creatinine (2009 formula) in top 10% of individuals by creatinine levels

2025-02-10

Genome-wide characterization of 54 urinary metabolites reveals molecular impact of kidney function.

Valo E, Richmond A et al.

Nat Commun

Urinary acetate to urinary creatinine ratio

2025-01-02

Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function.

Loeb GB, Kathail P et al.

Nat Genet

Estimated glomerular filtration rate (creatinine, cystatin c)

2024-09-10

Gene-vegetarianism interactions in calcium, estimated glomerular filtration rate, and testosterone identified in genome-wide analysis across 30 biomarkers.

Francis M, Westerman KE et al.

PLoS Genet

Sex hormone binding globulin levels (adjusted for BMI) x vegetarianism interaction

2024-07-11

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.

Scholz M, Horn K et al.

Nat Commun

Blood urea nitrogen levels

2024-01-18

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.

Hughes O, Bentley AR et al.

Cell Genom

Estimated glomerular filtration rate

2023-12-20

Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants.

Lee DJ, Moon JS et al.

Kidney Res Clin Pract

Estimated glomerular filtration rate

2023-11-03

Association of biological age with health outcomes and its modifiable factors.

Liu WS, You J et al.

Aging Cell

Biological age gap

2023-09-18

Genome-Wide Association Studies for Albuminuria of non-Diabetic Taiwanese Population.

Yang WS, Chuang GT et al.

Am J Nephrol

Albuminuria

2023-07-12

Genome-Wide Association Study of Chronic Kidney Disease Progression.

Robinson-Cohen C, Triozzi JL et al.

J Am Soc Nephrol

Estimated glomerular filtration rate

2023-06-01

Identification of Genetic Markers Linked to The Activity of Indoleamine 2,3-Dioxygenase and Kidney Function.

Kim HR, Jin HS et al.

Metabolites

Indoleamine 2,3-dioxygenase activity

2023-04-10