Active: Gallstone disease Clear all

GWAS 2023-09-13

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses.

Zhang L, Zhang W et al.

BMC Med

Despite epidemiological evidence associating gallstone disease (GSD) with cardiovascular disease (CV...

Gall stone disease or stroke

1858897

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-10

Genome-wide analysis identifies gallstone-susceptibility loci including genes regulating gastrointestinal motility.

Fairfield CJ, Drake TM et al.

Hepatology

Background and aims: Genome-wide association studies (GWAS) have identified several risk loci for ga...

Gallstone disease

Replicated

556754

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-28

Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry.

Bustos BI, Pérez-Palma E et al.

Sci Rep

Latin Americans and Chilean Amerindians have the highest prevalence of gallstone disease (GSD) and g...

Gallstone disease

Replicated

8830

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-30

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

Ferkingstad E, Oddsson A et al.

Nat Commun

Gallstones are responsible for one of the most common diseases in the Western world and are commonly...

Gallstone disease

764012

Participants

N/A

Studies

Details PubMed

GWAS 2018-10-16

Identification and replication of six new loci associated with gallstone disease.

Gellert-Kristensen H, Dalila N et al.

Hepatology

Gallstone disease is a common complex disease that confers a substantial economic burden on society....

Gallstone disease

Replicated

356996

Participants

N/A

Studies

Details PubMed

GWAS 2016-04-16

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.

Joshi AD, Andersson C et al.

Gastroenterology

Background & aims: A genome-wide association study (GWAS) of 280 cases identified the hepatic ch...

Gallstone disease

Replicated

147261

Participants

N/A

Studies

Details PubMed

GWAS 2007-07-15

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.

Buch S, Schafmayer C et al.

Nat Genet

With an overall prevalence of 10-20%, gallstone disease (cholelithiasis) represents one of the most ...

Gallstone disease

Replicated

3842

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses.

Zhang L, Zhang W et al.

BMC Med

Gall stone disease or stroke

2023-09-13

Genome-wide analysis identifies gallstone-susceptibility loci including genes regulating gastrointestinal motility.

Fairfield CJ, Drake TM et al.

Hepatology

Gallstone disease

2021-12-10

Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry.

Bustos BI, Pérez-Palma E et al.

Sci Rep

Gallstone disease

2019-01-28

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

Ferkingstad E, Oddsson A et al.

Nat Commun

Gallstone disease

2018-11-30

Identification and replication of six new loci associated with gallstone disease.

Gellert-Kristensen H, Dalila N et al.

Hepatology

Gallstone disease

2018-10-16

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.

Joshi AD, Andersson C et al.

Gastroenterology

Gallstone disease

2016-04-16

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.

Buch S, Schafmayer C et al.

Nat Genet

Gallstone disease

2007-07-15