Active: Gestational diabetes mellitus Clear all

GWAS 2025-05-05

Genetic architecture and risk prediction of gestational diabetes mellitus in Chinese pregnancies.

Gu Y, Zheng H et al.

Nat Commun

Gestational diabetes mellitus, a heritable metabolic disorder and the most common pregnancy-related ...

Gestational diabetes mellitus

Replicated

97563

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-19

Genome-wide association and Mendelian randomisation analysis among 30,699 Chinese pregnant women identifies novel genetic and molecular risk factors for gestational diabetes and glycaemic traits.

Zhen J, Gu Y et al.

Diabetologia

Aims/hypothesis: Gestational diabetes mellitus (GDM) is the most common disorder in pregnancy; howev...

Gestational diabetes mellitus

Replicated

28265

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-17

Metabolomic and genetic architecture of gestational diabetes subtypes.

Lee K, Kuang A et al.

Diabetologia

Aims/hypothesis: Physiological gestational diabetes mellitus (GDM) subtypes that may confer differen...

Gestational diabetes mellitus

8067

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-05

Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes.

Elliott A, Walters RK et al.

Nat Genet

Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16 million pr...

Gestational diabetes

Replicated

323181

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-12

Genome-wide analysis study of gestational diabetes mellitus and related pathogenic factors in a Chinese Han population.

Yue S, Pei L et al.

BMC Pregnancy Childbirth

Gestational diabetes mellitus (GDM) affects the metabolism of both the mother and fetus during and a...

Gestational diabetes mellitus

398

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-30

Associations between a polygenic risk score and the risk of gestational diabetes mellitus in a Chinese population: a case-control study.

Li Y, Yang M et al.

Endocr J

Our objective was to construct a polygenic risk score (PRS) and assess its utility and effectiveness...

Gestational diabetes mellitus

1700

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-15

Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort.

Fuller H, Iles MM et al.

Front Endocrinol (Lausanne)

Introduction: Gestational diabetes mellitus (GDM) is the most common pregnancy complication worldwid...

Omega-3 fatty acids levels

3354

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-26

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.

Pervjakova N, Moen GH et al.

Hum Mol Genet

Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and...

Gestational diabetes mellitus

358736

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-10

Interaction of Polygenetic Variants for Gestational Diabetes Mellitus Risk with Breastfeeding and Korean Balanced Diet to Influence Type 2 Diabetes Risk in Later Life in a Large Hospital-Based Cohort.

Park S

J Pers Med

The etiologies of gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) are simila...

Gestational diabetes mellitus

34340

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-03

A genome-wide association study of gestational diabetes mellitus in Chinese women.

Wu NN, Zhao D et al.

J Matern Fetal Neonatal Med

Recently, gestational diabetes mellitus (GDM) exhibits an obvious trend of increase in pregnant moth...

Diabetes (gestational)

218

Participants

N/A

Studies

Details PubMed

GWAS 2013-07-31

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.

Hayes MG, Urbanek M et al.

Diabetes

Maternal metabolism during pregnancy impacts the developing fetus, affecting offspring birth weight ...

Glycemic traits (pregnancy)

Replicated

7463

Participants

N/A

Studies

Details PubMed

GWAS 2013-04-11

New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.

Go MJ, Hwang JY et al.

J Hum Genet

Most recently, 1-h hyperglycemia has been recognized as an additional risk factor for type 2 diabete...

Glycemic traits

Replicated

14232

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic architecture and risk prediction of gestational diabetes mellitus in Chinese pregnancies.

Gu Y, Zheng H et al.

Nat Commun

Gestational diabetes mellitus

2025-05-05

Genome-wide association and Mendelian randomisation analysis among 30,699 Chinese pregnant women identifies novel genetic and molecular risk factors for gestational diabetes and glycaemic traits.

Zhen J, Gu Y et al.

Diabetologia

Gestational diabetes mellitus

2024-02-19

Metabolomic and genetic architecture of gestational diabetes subtypes.

Lee K, Kuang A et al.

Diabetologia

Gestational diabetes mellitus

2024-02-17

Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes.

Elliott A, Walters RK et al.

Nat Genet

Gestational diabetes

2024-01-05

Genome-wide analysis study of gestational diabetes mellitus and related pathogenic factors in a Chinese Han population.

Yue S, Pei L et al.

BMC Pregnancy Childbirth

Gestational diabetes mellitus

2023-12-12

Associations between a polygenic risk score and the risk of gestational diabetes mellitus in a Chinese population: a case-control study.

Li Y, Yang M et al.

Endocr J

Gestational diabetes mellitus

2023-09-30

Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort.

Fuller H, Iles MM et al.

Front Endocrinol (Lausanne)

Omega-3 fatty acids levels

2023-05-15

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.

Pervjakova N, Moen GH et al.

Hum Mol Genet

Gestational diabetes mellitus

2022-02-26

Interaction of Polygenetic Variants for Gestational Diabetes Mellitus Risk with Breastfeeding and Korean Balanced Diet to Influence Type 2 Diabetes Risk in Later Life in a Large Hospital-Based Cohort.

Park S

J Pers Med

Gestational diabetes mellitus

2021-11-10

A genome-wide association study of gestational diabetes mellitus in Chinese women.

Wu NN, Zhao D et al.

J Matern Fetal Neonatal Med

Diabetes (gestational)

2019-07-03

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.

Hayes MG, Urbanek M et al.

Diabetes

Glycemic traits (pregnancy)

2013-07-31

New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.

Go MJ, Hwang JY et al.

J Hum Genet

Glycemic traits

2013-04-11