Active: Glioblastoma Clear all

GWAS 2018-08-27

Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.

Ostrom QT, Kinnersley B et al.

Int J Cancer

Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM i...

Glioblastoma (age-stratified)

15094

Participants

N/A

Studies

Details PubMed

GWAS 2017-03-27

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.

Melin BS, Barnholtz-Sloan JS et al.

Nat Genet

Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, ...

Glioma

30659

Participants

N/A

Studies

Details PubMed

GWAS 2015-10-01

Genome-wide association study identifies multiple susceptibility loci for glioma.

Kinnersley B, Labussière M et al.

Nat Commun

Previous genome-wide association studies (GWASs) have shown that common genetic variation contribute...

Glioblastoma

Replicated

12431

Participants

N/A

Studies

Details PubMed

GWAS 2015-01-28

Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates.

Ruggiero D, Nappo S et al.

PLoS Genet

Cripto, the founding member of the EGF-CFC genes, plays an essential role in embryo development and ...

Cripto levels (serum)

Replicated

1589

Participants

N/A

Studies

Details PubMed

GWAS 2012-04-03

SSBP2 variants are associated with survival in glioblastoma patients.

Xiao Y, Decker PA et al.

Clin Cancer Res

Purpose: Glioblastoma is a devastating, incurable disease with few known prognostic factors. Here, w...

Glioblastoma

Replicated

749

Participants

N/A

Studies

Details PubMed

GWAS 2011-08-09

Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk.

Yang TH, Kon M et al.

BMC Med Genomics

Glioblastoma multiforme (GBM) tends to occur between the ages of 45 and 70. This relatively early on...

Glioma

4773

Participants

N/A

Studies

Details PubMed

GWAS 2009-07-05

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

Wrensch M, Jenkins RB et al.

Nat Genet

The causes of glioblastoma and other gliomas remain obscure. To discover new candidate genes influen...

Glioma (high-grade)

Replicated

5034

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.

Ostrom QT, Kinnersley B et al.

Int J Cancer

Glioblastoma (age-stratified)

2018-08-27

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.

Melin BS, Barnholtz-Sloan JS et al.

Nat Genet

Glioma

2017-03-27

Genome-wide association study identifies multiple susceptibility loci for glioma.

Kinnersley B, Labussière M et al.

Nat Commun

Glioblastoma

2015-10-01

Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates.

Ruggiero D, Nappo S et al.

PLoS Genet

Cripto levels (serum)

2015-01-28

SSBP2 variants are associated with survival in glioblastoma patients.

Xiao Y, Decker PA et al.

Clin Cancer Res

Glioblastoma

2012-04-03

Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk.

Yang TH, Kon M et al.

BMC Med Genomics

Glioma

2011-08-09

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

Wrensch M, Jenkins RB et al.

Nat Genet

Glioma (high-grade)

2009-07-05