Active: Homocysteine levels Clear all

GWAS 2023-07-29

GWAS of folate metabolism with gene-environment interaction analysis revealed the possible role of lifestyles in the control of blood folate metabolites in Japanese - the J-MICC Study.

Tsukamoto M, Hishida A et al.

J Epidemiol

The present genome-wide association study (GWAS) aimed to reveal the genetic loci associated with fo...

Homocysteine levels

Replicated

2836

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-11

Exome-Wide Association Study Identifies East Asian-Specific Missense Variant MTHFR C136T Influencing Homocysteine Levels in Chinese Populations RH: ExWAS of tHCY in a Chinese Population.

Liu T, Momin M et al.

Front Genet

Plasma total homocysteine (tHCY) is a known risk factor of a wide range of complex diseases. No geno...

Homocysteine levels

Replicated

5863

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-10

Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models.

Otani T, Noma H et al.

Eur J Hum Genet

Although the detection of predictive biomarkers is of particular importance for the development of a...

Progression-free survival response to gemcitabine in breast cancer

3289

Participants

N/A

Studies

Details PubMed

GWAS 2015-10-30

Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians.

Kim S, Nho K et al.

J Alzheimers Dis

Plasma homocysteine, a metabolite involved in key cellular methylation processes seems to be implica...

Plasma homocysteine levels

1858

Participants

N/A

Studies

Details PubMed

GWAS 2014-03-20

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.

Williams SR, Yang Q et al.

PLoS Genet

Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM)...

Plasma homocysteine levels (post-methionine load test)

4810

Participants

N/A

Studies

Details PubMed

GWAS 2013-07-03

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

van Meurs JB, Pare G et al.

Am J Clin Nutr

The strong observational association between total homocysteine (tHcy) concentrations and risk of co...

Homocysteine levels

44147

Participants

N/A

Studies

Details PubMed

GWAS 2010-02-13

Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults.

Lange LA, Croteau-Chonka DC et al.

Hum Mol Genet

Plasma homocysteine (Hcy) level is associated with cardiovascular disease and may play an etiologic ...

Homocysteine levels

Replicated

3465

Participants

N/A

Studies

Details PubMed

GWAS 2009-06-12

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.

Mälarstig A, Buil A et al.

Blood

Total plasma homocysteine concentration (tHcy) is a biomarker for atherothrombotic disease, but caus...

Homocysteine levels

Replicated

1625

Participants

N/A

Studies

Details PubMed

GWAS 2009-04-01

Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.

Paré G, Chasman DI et al.

Circ Cardiovasc Genet

Homocysteine is a sulfur amino acid whose plasma concentration has been associated with the risk of ...

Homocysteine levels

Replicated

14814

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

GWAS of folate metabolism with gene-environment interaction analysis revealed the possible role of lifestyles in the control of blood folate metabolites in Japanese - the J-MICC Study.

Tsukamoto M, Hishida A et al.

J Epidemiol

Homocysteine levels

2023-07-29

Exome-Wide Association Study Identifies East Asian-Specific Missense Variant MTHFR C136T Influencing Homocysteine Levels in Chinese Populations RH: ExWAS of tHCY in a Chinese Population.

Liu T, Momin M et al.

Front Genet

Homocysteine levels

2021-10-11

Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models.

Otani T, Noma H et al.

Eur J Hum Genet

Progression-free survival response to gemcitabine in breast cancer

2018-09-10

Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians.

Kim S, Nho K et al.

J Alzheimers Dis

Plasma homocysteine levels

2015-10-30

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.

Williams SR, Yang Q et al.

PLoS Genet

Plasma homocysteine levels (post-methionine load test)

2014-03-20

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

van Meurs JB, Pare G et al.

Am J Clin Nutr

Homocysteine levels

2013-07-03

Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults.

Lange LA, Croteau-Chonka DC et al.

Hum Mol Genet

Homocysteine levels

2010-02-13

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.

Mälarstig A, Buil A et al.

Blood

Homocysteine levels

2009-06-12

Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.

Paré G, Chasman DI et al.

Circ Cardiovasc Genet

Homocysteine levels

2009-04-01