Active: Hyperglycemia Clear all

GWAS 2024-02-29

Genetic Determinants of Thiazide-Induced Hyperuricemia, Hyperglycemia, and Urinary Electrolyte Disturbances - A Genome-Wide Evaluation of the UK Biobank.

Asiimwe IG, Walker L et al.

Clin Pharmacol Ther

Thiazide diuretics, widely used in hypertension, cause a variety of adverse reactions, including hyp...

Blood Glucose variance level in bendroflumethiazide treated hypertension

95493

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-26

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

Park S, Liu M

Nutrients

The controversy over the link between noodle consumption and metabolic syndrome (MetS) persists. Usi...

Noodle intake

58701

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-04

Height-Related Polygenic Variants Are Associated with Metabolic Syndrome Risk and Interact with Energy Intake and a Rice-Main Diet to Influence Height in KoGES.

Park S

Nutrients

Adult height is inversely related to metabolic syndrome (MetS) risk, but its genetic impacts have no...

Height

Replicated

72484

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-23

Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses.

Mansour A, Mousa M et al.

Front Endocrinol (Lausanne)

Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disorder in which concomitant insulin resist...

Diabetic retinopathy in type 2 diabetes

310

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-26

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

Park S

Foods

A plant-based diet (PBD) has been reported to be linked to metabolic syndrome (MetS) risk in observa...

Highly plant-based diet

58701

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-27

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Liu M, Park S

Antioxidants (Basel)

Excessive oxidative stress can contribute to metabolic syndrome (MetS), and antioxidants can protect...

Vitamin C intake

52676

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-21

Regular exercise, alcohol consumption, and smoking interact with the polygenetic risk scores involved in insulin sensitivity and secretion for the risk of concurrent hyperglycemia, hypertension, and dyslipidemia.

Zhou JY, Park S

Nutrition

Objectives: 3GO, defined as the simultaneous presence of hypertension, hyperglycemia, and dyslipidem...

3GO (hypertension, hyperglycemia and dyslipidemia)

14725

Participants

N/A

Studies

Details PubMed

GWAS 2018-10-16

Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women.

Jung SY, Mancuso N et al.

Cancer Prev Res (Phila)

Insulin resistance (IR)-related genetic variants are possibly associated with breast cancer, and the...

Hyperglycemia

11794

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-29

Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results from the Atherosclerosis Risk in Communities Study.

Loomis SJ, Li M et al.

Diabetes

Fructosamine and glycated albumin are potentially useful alternatives to hemoglobin A1c (HbA1c) as d...

Percent glycated albumin

Replicated

11663

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-09

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.

Singh S, McDonough CW et al.

J Am Heart Assoc

Thiazide and thiazide-like diuretics are first-line medications for treating uncomplicated hypertens...

Change in glucose in response to thiazide diuretic treatment in hypertension

Replicated

672

Participants

N/A

Studies

Details PubMed

GWAS 2016-02-23

Genetic analysis of advanced glycation end products in the DHS MIND study.

Adams JN, Raffield LM et al.

Gene

Advanced glycation end-products (AGEs) are a diverse group of molecules produced by the non-enzymati...

Soluble receptor for advanced glycation end-product levels

506

Participants

N/A

Studies

Details PubMed

GWAS 2013-12-04

Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).

An P, Miljkovic I et al.

Metabolism

Objective: Glycated hemoglobin (HbA1c) is a stable index of chronic glycemic status and hyperglycemi...

Glycated hemoglobin levels

Replicated

51910

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic Determinants of Thiazide-Induced Hyperuricemia, Hyperglycemia, and Urinary Electrolyte Disturbances - A Genome-Wide Evaluation of the UK Biobank.

Asiimwe IG, Walker L et al.

Clin Pharmacol Ther

Blood Glucose variance level in bendroflumethiazide treated hypertension

2024-02-29

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

Park S, Liu M

Nutrients

Noodle intake

2023-04-26

Park S

Nutrients

Height

2023-04-04

Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses.

Mansour A, Mousa M et al.

Front Endocrinol (Lausanne)

Diabetic retinopathy in type 2 diabetes

2023-03-23

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

Park S

Foods

Highly plant-based diet

2023-01-26

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Liu M, Park S

Antioxidants (Basel)

Vitamin C intake

2022-04-27

Regular exercise, alcohol consumption, and smoking interact with the polygenetic risk scores involved in insulin sensitivity and secretion for the risk of concurrent hyperglycemia, hypertension, and dyslipidemia.

Zhou JY, Park S

Nutrition

3GO (hypertension, hyperglycemia and dyslipidemia)

2021-07-21

Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women.

Jung SY, Mancuso N et al.

Cancer Prev Res (Phila)

Hyperglycemia

2018-10-16

Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results from the Atherosclerosis Risk in Communities Study.

Loomis SJ, Li M et al.

Diabetes

Percent glycated albumin

2018-05-29

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.

Singh S, McDonough CW et al.

J Am Heart Assoc

Change in glucose in response to thiazide diuretic treatment in hypertension

2018-03-09

Genetic analysis of advanced glycation end products in the DHS MIND study.

Adams JN, Raffield LM et al.

Gene

Soluble receptor for advanced glycation end-product levels

2016-02-23

Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).

An P, Miljkovic I et al.

Metabolism

Glycated hemoglobin levels

2013-12-04