Active: Hyperopia Clear all

GWAS 2021-04-08

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia.

Tideman JWL, Pärssinen O et al.

JAMA Ophthalmol

Importance: Uncertainty currently exists about whether the same genetic variants are associated with...

Low myopia

32613

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-11

Association analysis of exome variants and refraction, axial length, and corneal curvature in a European-American population.

Vergara C, Bomotti SM et al.

Hum Mutat

Refractive errors, myopia, and hyperopia are common visual disorders greatly affecting older individ...

Axial length

874

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-18

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci.

Simpson CL, Wojciechowski R et al.

PLoS One

Refractive error (RE) is a complex, multifactorial disorder characterized by a mismatch between the ...

Hyperopia

Replicated

20933

Participants

N/A

Studies

Details PubMed

GWAS 2013-08-08

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.

Cheng CY, Schache M et al.

Am J Hum Genet

Refractive errors are common eye disorders of public health importance worldwide. Ocular axial lengt...

Axial length

Replicated

20747

Participants

N/A

Studies

Details PubMed

GWAS 2010-09-12

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.

Hysi PG, Young TL et al.

Nat Genet

Myopia and hyperopia are at opposite ends of the continuum of refraction, the measure of the eye's a...

Refractive error

Replicated

17684

Participants

N/A

Studies

Details PubMed

GWAS 2010-09-12

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.

Solouki AM, Verhoeven VJ et al.

Nat Genet

Refractive errors are the most common ocular disorders worldwide and may lead to blindness. Although...

Refractive error

Replicated

15608

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia.

Tideman JWL, Pärssinen O et al.

JAMA Ophthalmol

Low myopia

2021-04-08

Association analysis of exome variants and refraction, axial length, and corneal curvature in a European-American population.

Vergara C, Bomotti SM et al.

Hum Mutat

Axial length

2018-09-11

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci.

Simpson CL, Wojciechowski R et al.

PLoS One

Hyperopia

2014-09-18

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.

Cheng CY, Schache M et al.

Am J Hum Genet

Axial length

2013-08-08

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.

Hysi PG, Young TL et al.

Nat Genet

Refractive error

2010-09-12

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.

Solouki AM, Verhoeven VJ et al.

Nat Genet

Refractive error

2010-09-12