Active: Hypertrophic cardiomyopathy Clear all

GWAS 2025-02-18

Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.

Tadros R, Zheng SL et al.

Nat Genet

Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality with both monogen...

Hypertrophic cardiomyopathy

74259

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-30

Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy.

Ning C, Fan L et al.

Nat Commun

Left ventricular regional wall thickness (LVRWT) is an independent predictor of morbidity and mortal...

Left ventricular end systole inferoseptal wall thickness

41984

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-05

Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy.

Yu M, Harper AR et al.

Circ Genom Precis Med

A large proportion of genetic risk remains unexplained for structural heart disease involving the in...

Interventricular septum cross-sectional area

306

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-24

Identification of Novel Genetic Variants and Comorbidities Associated With ICD-10-Based Diagnosis of Hypertrophic Cardiomyopathy Using the UK Biobank Cohort.

Gyftopoulos A, Chen YJ et al.

Front Genet

Objectives: To identify previously unrecognized genetic variants and clinical variables associated w...

Hypertrophic cardiomyopathy (ICD-10 coded)

7623

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-25

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity.

Harper AR, Goel A et al.

Nat Genet

Hypertrophic cardiomyopathy (HCM) is a common, serious, genetic heart disorder. Rare pathogenic vari...

Hypertrophic cardiomyopathy

Replicated

58537

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-19

Formin homology 2 domain containing 3 variants associated with hypertrophic cardiomyopathy.

Wooten EC, Hebl VB et al.

Circ Cardiovasc Genet

Incomplete penetrance and variable expression of hypertrophic cardiomyopathy (HCM) is well appreciat...

Hypertrophic cardiomyopathy

Replicated

3335

Participants

N/A

Studies

Details PubMed

Title

Author

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Disease/Trait

Date

Actions

Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.

Tadros R, Zheng SL et al.

Nat Genet

Hypertrophic cardiomyopathy

2025-02-18

Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy.

Ning C, Fan L et al.

Nat Commun

Left ventricular end systole inferoseptal wall thickness

2023-11-30

Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy.

Yu M, Harper AR et al.

Circ Genom Precis Med

Interventricular septum cross-sectional area

2023-04-05

Identification of Novel Genetic Variants and Comorbidities Associated With ICD-10-Based Diagnosis of Hypertrophic Cardiomyopathy Using the UK Biobank Cohort.

Gyftopoulos A, Chen YJ et al.

Front Genet

Hypertrophic cardiomyopathy (ICD-10 coded)

2022-05-24

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity.

Harper AR, Goel A et al.

Nat Genet

Hypertrophic cardiomyopathy

2021-01-25

Formin homology 2 domain containing 3 variants associated with hypertrophic cardiomyopathy.

Wooten EC, Hebl VB et al.

Circ Cardiovasc Genet

Hypertrophic cardiomyopathy

2012-12-19