Active: IgA levels Clear all

GWAS 2023-06-19

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.

Kiryluk K, Sanchez-Rodriguez E et al.

Nat Genet

IgA nephropathy (IgAN) is a progressive form of kidney disease defined by glomerular deposition of I...

IgA nephropathy

25852

Participants

N/A

Studies

Details PubMed

GWAS 2017-06-19

Identification of sequence variants influencing immunoglobulin levels.

Jonsson S, Sveinbjornsson G et al.

Nat Genet

Immunoglobulins are the effector molecules of the adaptive humoral immune system. In a genome-wide a...

IgA levels

Replicated

19034

Participants

N/A

Studies

Details PubMed

GWAS 2014-03-27

IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L.

Viktorin A, Frankowiack M et al.

Hum Mol Genet

In a broad attempt to improve the understanding of the genetic regulation of serum IgA levels, the h...

Serum IgA levels

Replicated

12402

Participants

N/A

Studies

Details PubMed

GWAS 2012-08-03

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers.

Yang C, Jie W et al.

Immunogenetics

IgA is an important factor in our immune system. There are many diseases associated with it, such as...

IgA levels

Replicated

3495

Participants

N/A

Studies

Details PubMed

GWAS 2011-12-25

A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.

Yu XQ, Li M et al.

Nat Genet

We performed a two-stage genome-wide association study of IgA nephropathy (IgAN) in Han Chinese, wit...

IgA nephropathy

Replicated

11871

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.

Kiryluk K, Sanchez-Rodriguez E et al.

Nat Genet

IgA nephropathy

2023-06-19

Identification of sequence variants influencing immunoglobulin levels.

Jonsson S, Sveinbjornsson G et al.

Nat Genet

IgA levels

2017-06-19

IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L.

Viktorin A, Frankowiack M et al.

Hum Mol Genet

Serum IgA levels

2014-03-27

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers.

Yang C, Jie W et al.

Immunogenetics

IgA levels

2012-08-03

A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.

Yu XQ, Li M et al.

Nat Genet

IgA nephropathy

2011-12-25