Active: IgG glycosylation Clear all

GWAS 2022-03-24

Genetic regulation of post-translational modification of two distinct proteins.

Landini A, Trbojević-Akmačić I et al.

Nat Commun

Post-translational modifications diversify protein functions and dynamically coordinate their signal...

Immunoglobulin N-glycan 6 levels

2020

Participants

N/A

Studies

Details PubMed

GWAS 2020-02-19

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.

Klarić L, Tsepilov YA et al.

Sci Adv

Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan moiety, th...

IgG N-glycosylation phenotypes (multivariate analysis)

Replicated

10478

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-15

Defining the genetic control of human blood plasma N-glycome using genome-wide association study.

Sharapov SZ, Tsepilov YA et al.

Hum Mol Genet

Glycosylation is a common post-translational modification of proteins. Glycosylation is associated w...

N-glycan levels

Replicated

3975

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-26

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.

Wahl A, van den Akker E et al.

Front Immunol

Immunoglobulin G (IgG), a glycoprotein secreted by plasma B-cells, plays a major role in the human a...

IgG glycosylation patterns

Replicated

3659

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-31

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Lauc G, Huffman JE et al.

PLoS Genet

Glycosylation of immunoglobulin G (IgG) influences IgG effector function by modulating binding to Fc...

IgG glycosylation

2247

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic regulation of post-translational modification of two distinct proteins.

Landini A, Trbojević-Akmačić I et al.

Nat Commun

Immunoglobulin N-glycan 6 levels

2022-03-24

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.

Klarić L, Tsepilov YA et al.

Sci Adv

IgG N-glycosylation phenotypes (multivariate analysis)

2020-02-19

Defining the genetic control of human blood plasma N-glycome using genome-wide association study.

Sharapov SZ, Tsepilov YA et al.

Hum Mol Genet

N-glycan levels

2019-06-15

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.

Wahl A, van den Akker E et al.

Front Immunol

IgG glycosylation patterns

2018-02-26

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Lauc G, Huffman JE et al.

PLoS Genet

IgG glycosylation

2013-01-31