Active: Metabolic syndrome Clear all

GWAS 2024-09-30

Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome.

Park S, Kim S et al.

Nat Genet

Metabolic syndrome (MetS) is a complex hereditary condition comprising various metabolic traits as r...

Metabolic syndrome

1384348

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-25

A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population.

Ho CY, Lee JI et al.

Nutrients

The purpose of this study was to investigate genetic factors associated with metabolic syndrome (Met...

Metabolic syndrome

107230

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-18

A Cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin.

Sarsani V, Brotman SM et al.

HGG Adv

Previous genome-wide association studies (GWASs) for adiponectin, a complex trait linked to type 2 d...

Adiponectin levels

Replicated

81993

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-26

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

Park S, Liu M

Nutrients

The controversy over the link between noodle consumption and metabolic syndrome (MetS) persists. Usi...

Noodle intake

58701

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-04

Height-Related Polygenic Variants Are Associated with Metabolic Syndrome Risk and Interact with Energy Intake and a Rice-Main Diet to Influence Height in KoGES.

Park S

Nutrients

Adult height is inversely related to metabolic syndrome (MetS) risk, but its genetic impacts have no...

Height

Replicated

72484

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-18

Association of polygenic risk scores for insulin resistance risk and their interaction with a plant-based diet, especially fruits, vitamin C, and flavonoid intake, in Asian adults.

Park S

Nutrition

Objectives: Insulin resistance is a common risk factor for metabolic syndrome (MetS), leading to typ...

Insulin resistance

58701

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-26

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

Park S

Foods

A plant-based diet (PBD) has been reported to be linked to metabolic syndrome (MetS) risk in observa...

Highly plant-based diet

58701

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-24

Gamma-glutamyl-leucine levels are causally associated with elevated cardio-metabolic risks.

Wu Q, Li J et al.

Front Nutr

Objective: Gamma-glutamyl dipeptides are bioactive peptides involved in inflammation, oxidative stre...

Gamma-glutamylleucine levels

Replicated

1289

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-05

Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes.

Zhou W, Sun J et al.

Mol Psychiatry

Antipsychotic-induced metabolic syndrome (APs-induced Mets) is the most common adverse drug reaction...

Antipsychotic-induced metabolic syndrome in schizophrenia

939

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-27

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Liu M, Park S

Antioxidants (Basel)

Excessive oxidative stress can contribute to metabolic syndrome (MetS), and antioxidants can protect...

Vitamin C intake

52676

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-28

Polygenetic Variants Related to Osteoarthritis Risk and Their Interactions with Energy, Protein, Fat, and Alcohol Intake in Adults in a Large Cohort.

Park S

Diagnostics (Basel)

Osteoarthritis (OA) is increasing globally, especially among elderly Asian women, and its increase m...

Osteoarthritis

5430

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-14

Polymorphism rs10105606 of <i>LPL</i> as a Novel Risk Factor for Microalbuminuria.

Lim ZW, Chen WL

J Inflamm Res

Introduction: An important clinical feature of metabolic syndrome is abdominal obesity. Microalbumin...

Microalbuminuria

1325

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome.

Park S, Kim S et al.

Nat Genet

Metabolic syndrome

2024-09-30

A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population.

Ho CY, Lee JI et al.

Nutrients

Metabolic syndrome

2023-12-25

A Cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin.

Sarsani V, Brotman SM et al.

HGG Adv

Adiponectin levels

2023-10-18

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

Park S, Liu M

Nutrients

Noodle intake

2023-04-26

Park S

Nutrients

Height

2023-04-04

Association of polygenic risk scores for insulin resistance risk and their interaction with a plant-based diet, especially fruits, vitamin C, and flavonoid intake, in Asian adults.

Park S

Nutrition

Insulin resistance

2023-02-18

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

Park S

Foods

Highly plant-based diet

2023-01-26

Gamma-glutamyl-leucine levels are causally associated with elevated cardio-metabolic risks.

Wu Q, Li J et al.

Front Nutr

Gamma-glutamylleucine levels

2022-11-24

Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes.

Zhou W, Sun J et al.

Mol Psychiatry

Antipsychotic-induced metabolic syndrome in schizophrenia

2022-09-05

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Liu M, Park S

Antioxidants (Basel)

Vitamin C intake

2022-04-27

Polygenetic Variants Related to Osteoarthritis Risk and Their Interactions with Energy, Protein, Fat, and Alcohol Intake in Adults in a Large Cohort.

Park S

Diagnostics (Basel)

Osteoarthritis

2022-01-28

Polymorphism rs10105606 of <i>LPL</i> as a Novel Risk Factor for Microalbuminuria.

Lim ZW, Chen WL

J Inflamm Res

Microalbuminuria

2021-12-14