Active: Myocardial infarction Clear all

GWAS 2025-03-31

A genome-wide association study of imaging-defined atherosclerosis.

Gummesson A, Lundmark P et al.

Nat Commun

Imaging-defined atherosclerosis represents an intermediate phenotype of atherosclerotic cardiovascul...

Coronary artery calcification

26000

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-10

Uncovering myocardial infarction genetic signatures using GWAS exploration in Saudi and European cohorts.

Al-Ali AK, Al-Rubaish AM et al.

Sci Rep

Genome-wide association studies (GWAS) have yielded significant insights into the genetic architectu...

Myocardial infarction

6274

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-01

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Genetic studies of platelet reactivity (PR) phenotypes may identify novel antiplatelet drug targets....

Predicted platelet reactivity

29806

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-29

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.

Adlam D, Berrandou TE et al.

Nat Genet

Spontaneous coronary artery dissection (SCAD) is an understudied cause of myocardial infarction prim...

Spontaneous coronary artery dissection

11209

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-15

Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes.

Villaplana-Velasco A, Pigeyre M et al.

Commun Biol

There is increasing evidence that the complexity of the retinal vasculature measured as fractal dime...

Retinal vascular fractal dimension (right eye)

Replicated

44176

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-02

Shared genetic risk factors and causal association between psoriasis and coronary artery disease.

Patrick MT, Li Q et al.

Nat Commun

Psoriasis and coronary artery disease (CAD) are related comorbidities that are well established, but...

Psoriasis or coronary artery disease

211665

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-06

Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population.

Sethi A, Taylor DL et al.

Front Cardiovasc Med

Calcification of large arteries is a high-risk factor in the development of cardiovascular diseases,...

Abdominal aortic calcification levels

Replicated

72989

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-08

ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study.

Lu Z, Zhang Y et al.

Transl Psychiatry

QTc interval prolongation is one of the most common antipsychotic-induced side effects which could l...

Antipsychotic drug-induced QTc interval change in schizophrenia

2040

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-05

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.

Trompet S, Postmus I et al.

Front Pharmacol

The pharmacogenetic effect on cardiovascular disease reduction in response to statin treatment has o...

Myocardial infraction risk reduction in statin users

Replicated

12294

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-15

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Georges A, Yang ML et al.

Nat Commun

Fibromuscular dysplasia (FMD) is an arteriopathy associated with hypertension, stroke and myocardial...

Fibromuscular dysplasia

8656

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-07

Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS).

McDonough CW, Warren HR et al.

Clin Pharmacol Ther

We sought to identify genome-wide variants influencing antihypertensive drug response and adverse ca...

Adverse cardiovascular outcome x beta blockers interaction in hypertension

9195

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-07

Genome-wide association study of cardiac troponin I in the general population.

Moksnes MR, Røsjø H et al.

Hum Mol Genet

Circulating cardiac troponin proteins are associated with structural heart disease and predict incid...

Change in high-sensitivity cardiac troponin I concentration

5178

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study of imaging-defined atherosclerosis.

Gummesson A, Lundmark P et al.

Nat Commun

Coronary artery calcification

2025-03-31

Uncovering myocardial infarction genetic signatures using GWAS exploration in Saudi and European cohorts.

Al-Ali AK, Al-Rubaish AM et al.

Sci Rep

Myocardial infarction

2023-12-10

A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk.

Verdier H, Thomas P et al.

Blood

Predicted platelet reactivity

2023-11-01

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.

Adlam D, Berrandou TE et al.

Nat Genet

Spontaneous coronary artery dissection

2023-05-29

Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes.

Villaplana-Velasco A, Pigeyre M et al.

Commun Biol

Retinal vascular fractal dimension (right eye)

2023-05-15

Shared genetic risk factors and causal association between psoriasis and coronary artery disease.

Patrick MT, Li Q et al.

Nat Commun

Psoriasis or coronary artery disease

2022-11-02

Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population.

Sethi A, Taylor DL et al.

Front Cardiovasc Med

Abdominal aortic calcification levels

2022-10-06

ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study.

Lu Z, Zhang Y et al.

Transl Psychiatry

Antipsychotic drug-induced QTc interval change in schizophrenia

2022-02-08

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.

Trompet S, Postmus I et al.

Front Pharmacol

Myocardial infraction risk reduction in statin users

2022-01-05

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Georges A, Yang ML et al.

Nat Commun

Fibromuscular dysplasia

2021-10-15

Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS).

McDonough CW, Warren HR et al.

Clin Pharmacol Ther

Adverse cardiovascular outcome x beta blockers interaction in hypertension

2021-07-07

Genome-wide association study of cardiac troponin I in the general population.

Moksnes MR, Røsjø H et al.

Hum Mol Genet

Change in high-sensitivity cardiac troponin I concentration

2021-05-07