Active: Pneumonia Clear all

GWAS 2024-10-22

Variants in the β-globin Locus are Associated with Pneumonia in African American Children.

Halligan NLN, Hanks SC et al.

HGG Adv

In African American adults, the strongest genetic predictor of pneumonia appears to be the A allele ...

Pneumonia

1000

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-14

Genome-Wide Association Study of COVID-19 Outcomes Reveals Novel Host Genetic Risk Loci in the Serbian Population.

Zecevic M, Kotur N et al.

Front Genet

Host genetics, an important contributor to the COVID-19 clinical susceptibility and severity, curren...

COVID-19 related pneumonia

128

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-29

The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness.

Reay WR, Geaghan MP et al.

Nat Commun

Pneumonia remains one of the leading causes of death worldwide. In this study, we use genome-wide me...

Pneumonia

391044

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-11

Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population.

Chamnanphon M, Pongpanich M et al.

J Hum Genet

Host genetic factors have been shown to play a role in SARs-CoV-2 infection in diverse populations. ...

COVID-19

222

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-03

Genetic Susceptibility to Pneumonia: A GWAS Meta-Analysis Between the UK Biobank and FinnGen.

Campos AI, Kho P et al.

Twin Res Hum Genet

Pneumonia is a respiratory condition with complex etiology. Host genetic variation is thought to con...

Pneumonia

550375

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-16

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.

Ahluwalia TS, Eliasen AU et al.

Nat Commun

Asthma with severe exacerbation is the most common cause of hospitalization among young children. We...

Childhood asthma with severe exacerbations

68281

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-13

Host genetic effects in pneumonia.

Chen HH, Shaw DM et al.

Am J Hum Genet

Given the coronavirus disease 2019 (COVID-19) pandemic, investigations into host susceptibility to i...

Pneumonia

Replicated

552161

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-15

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.

Lees JA, Ferwerda B et al.

Nat Commun

Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening i...

Bacterial meningitis

5985

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-14

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relation to chronic lymphocytic leukemia.

Chen X, Gustafsson S et al.

Hum Mol Genet

Phosphorylcholine (PC) is an epitope on oxidized low-density lipoprotein (oxLDL), apoptotic cells an...

Immunoglobulin M against phosphorylcholine (IgM anti-PC) levels

Replicated

3648

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-19

Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.

Tian C, Hromatka BS et al.

Nat Commun

Infectious diseases have a profound impact on our health and many studies suggest that host genetics...

Chickenpox

123751

Participants

N/A

Studies

Details PubMed

GWAS 2016-06-02

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.

Rautanen A, Pirinen M et al.

Am J Hum Genet

Bacteremia (bacterial bloodstream infection) is a major cause of illness and death in sub-Saharan Af...

Pneumococcal bacteremia

Replicated

4555

Participants

N/A

Studies

Details PubMed

GWAS 2015-03-11

Genome-wide genetic investigation of serological measures of common infections.

Rubicz R, Yolken R et al.

Eur J Hum Genet

Populations and individuals differ in susceptibility to infections because of a number of factors, i...

Antibody level in response to infection

1932

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Variants in the β-globin Locus are Associated with Pneumonia in African American Children.

Halligan NLN, Hanks SC et al.

HGG Adv

Pneumonia

2024-10-22

Genome-Wide Association Study of COVID-19 Outcomes Reveals Novel Host Genetic Risk Loci in the Serbian Population.

Zecevic M, Kotur N et al.

Front Genet

COVID-19 related pneumonia

2022-07-14

The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness.

Reay WR, Geaghan MP et al.

Nat Commun

Pneumonia

2022-06-29

Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population.

Chamnanphon M, Pongpanich M et al.

J Hum Genet

COVID-19

2022-01-11

Genetic Susceptibility to Pneumonia: A GWAS Meta-Analysis Between the UK Biobank and FinnGen.

Campos AI, Kho P et al.

Twin Res Hum Genet

Pneumonia

2021-08-03

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.

Ahluwalia TS, Eliasen AU et al.

Nat Commun

Childhood asthma with severe exacerbations

2020-12-16

Host genetic effects in pneumonia.

Chen HH, Shaw DM et al.

Am J Hum Genet

Pneumonia

2020-12-13

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.

Lees JA, Ferwerda B et al.

Nat Commun

Bacterial meningitis

2019-05-15

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relation to chronic lymphocytic leukemia.

Chen X, Gustafsson S et al.

Hum Mol Genet

Immunoglobulin M against phosphorylcholine (IgM anti-PC) levels

2018-03-14

Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.

Tian C, Hromatka BS et al.

Nat Commun

Chickenpox

2017-09-19

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.

Rautanen A, Pirinen M et al.

Am J Hum Genet

Pneumococcal bacteremia

2016-06-02

Genome-wide genetic investigation of serological measures of common infections.

Rubicz R, Yolken R et al.

Eur J Hum Genet

Antibody level in response to infection

2015-03-11