Active: Proinsulin levels Clear all

GWAS 2023-02-20

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

The co-occurrence of migraine and glycemic traits has long been reported in observational epidemiolo...

Migraine or 2-hr glucose levels

937810

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-16

Genome-wide association study of fasting proinsulin, fasting insulin, 2-hour postprandial proinsulin, and 2-hour postprandial insulin in Chinese Han people.

Lin L, Quan H et al.

Endokrynol Pol

Introduction: Fasting proinsulin (FPI) and fasting insulin (FI) have been demonstrated to be associa...

Fasting proinsulin levels in prediabetes

451

Participants

N/A

Studies

Details PubMed

GWAS 2012-12-23

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.

Huyghe JR, Jackson AU et al.

Nat Genet

Insulin secretion has a crucial role in glucose homeostasis, and failure to secrete sufficient insul...

Fasting blood proinsulin levels

8229

Participants

N/A

Studies

Details PubMed

GWAS 2011-08-26

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Strawbridge RJ, Dupuis J et al.

Diabetes

Objective: Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin ...

Proinsulin levels

Replicated

27079

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

Migraine or 2-hr glucose levels

2023-02-20

Genome-wide association study of fasting proinsulin, fasting insulin, 2-hour postprandial proinsulin, and 2-hour postprandial insulin in Chinese Han people.

Lin L, Quan H et al.

Endokrynol Pol

Fasting proinsulin levels in prediabetes

2022-08-16

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.

Huyghe JR, Jackson AU et al.

Nat Genet

Fasting blood proinsulin levels

2012-12-23

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Strawbridge RJ, Dupuis J et al.

Diabetes

Proinsulin levels

2011-08-26