Active: Pulmonary arterial hypertension Clear all

GWAS 2024-03-12

Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.

Liley J, Newnham M et al.

Am J Respir Crit Care Med

Rationale: Chronic thromboembolic pulmonary hypertension involves the formation and nonresolution of...

Chronic thromboembolic pulmonary hypertension

12264

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-08

Identification of novel genetic variants, including PIM1 and LINC01491, with ICD-10 based diagnosis of pulmonary arterial hypertension in the UK Biobank cohort.

Pu A, Ramani G et al.

Front Drug Discov (Lausanne)

Pulmonary arterial hypertension (PAH) is characterized by remodeling and narrowing of the pulmonary ...

ICD10 127.0 pulmonary arterial hypertension

25143

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-07

Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.

Thomeas-McEwing V, Psotka MA et al.

Pharmacogenet Genomics

Objective: Prostacyclin infusion for pulmonary arterial hypertension (PAH) is an effective therapy w...

Treprostinil dose in pulmonary arterial hypertension

Participants

N/A

Studies

Details PubMed

GWAS 2018-12-05

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ, Batai K et al.

Lancet Respir Med

Rare genetic variants cause pulmonary arterial hypertension, but the contribution of common genetic ...

Pulmonary arterial hypertension

11744

Participants

N/A

Studies

Details PubMed

GWAS 2017-08-24

A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population.

Kimura M, Tamura Y et al.

Oncotarget

Pulmonary arterial hypertension (PAH) is a lethal disease that often affects the young. Although Bon...

Pulmonary arterial hypertension

Replicated

3037

Participants

N/A

Studies

Details PubMed

GWAS 2013-03-17

Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.

Germain M, Eyries M et al.

Nat Genet

Pulmonary arterial hypertension (PAH) is a rare, severe disease resulting from progressive obliterat...

Pulmonary arterial hypertension (without BMPR2 mutations)

Replicated

2150

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.

Liley J, Newnham M et al.

Am J Respir Crit Care Med

Chronic thromboembolic pulmonary hypertension

2024-03-12

Identification of novel genetic variants, including PIM1 and LINC01491, with ICD-10 based diagnosis of pulmonary arterial hypertension in the UK Biobank cohort.

Pu A, Ramani G et al.

Front Drug Discov (Lausanne)

ICD10 127.0 pulmonary arterial hypertension

2023-02-08

Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.

Thomeas-McEwing V, Psotka MA et al.

Pharmacogenet Genomics

Treprostinil dose in pulmonary arterial hypertension

2022-04-07

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ, Batai K et al.

Lancet Respir Med

Pulmonary arterial hypertension

2018-12-05

A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population.

Kimura M, Tamura Y et al.

Oncotarget

Pulmonary arterial hypertension

2017-08-24

Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.

Germain M, Eyries M et al.

Nat Genet

Pulmonary arterial hypertension (without BMPR2 mutations)

2013-03-17