Active: Resistant hypertension Clear all

GWAS 2023-12-13

Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program.

Armstrong ND, Srinivasasainagendra V et al.

Front Genet

Introduction: Apparent treatment-resistant hypertension (aTRH) is characterized by the use of four o...

Apparent treatment-resistant hypertension

7129

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-07

Genome-wide association studies categorized by class of anti-hypertensive drugs reveal complex pathogenesis of hypertension with drug resistance.

Yamazaki K, Terao C et al.

Clin Pharmacol Ther

Resistant hypertension is defined as uncontrolled blood pressure (BP) despite the use of three or mo...

Resistance to antihypertensive treatment in hypertension

31989

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-30

A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension.

Xiao X, Li R et al.

BMC Med

Compared with patients who require fewer antihypertensive agents, those with apparent treatment-resi...

Apparent treatment-resistant hypertension

1358

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-30

A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population.

Takahashi Y, Yamazaki K et al.

Sci Rep

Numerous genetic variants associated with hypertension and blood pressure are known, but there is a ...

Resistant hypertension

24001

Participants

N/A

Studies

Details PubMed

GWAS 2019-09-23

Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group.

Irvin MR, Sitlani CM et al.

Am J Hypertens

Only a handful of genetic discovery efforts in apparent treatment-resistant hypertension (aTRH) have...

Resistant hypertension

Replicated

17849

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-20

Genome-wide association analysis of common genetic variants of resistant hypertension.

El Rouby N, McDonough CW et al.

Pharmacogenomics J

Resistant hypertension (RHTN), defined as uncontrolled blood pressure (BP) ≥ 140/90 using three or m...

Resistant hypertension

Replicated

4196

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-01

Genome-wide study of resistant hypertension identified from electronic health records.

Dumitrescu L, Ritchie MD et al.

PLoS One

Resistant hypertension is defined as high blood pressure that remains above treatment goals in spite...

Resistance to antihypertensive treatment in hypertension

3706

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program.

Armstrong ND, Srinivasasainagendra V et al.

Front Genet

Apparent treatment-resistant hypertension

2023-12-13

Genome-wide association studies categorized by class of anti-hypertensive drugs reveal complex pathogenesis of hypertension with drug resistance.

Yamazaki K, Terao C et al.

Clin Pharmacol Ther

Resistance to antihypertensive treatment in hypertension

2023-05-07

A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension.

Xiao X, Li R et al.

BMC Med

Apparent treatment-resistant hypertension

2022-11-30

A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population.

Takahashi Y, Yamazaki K et al.

Sci Rep

Resistant hypertension

2021-09-30

Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group.

Irvin MR, Sitlani CM et al.

Am J Hypertens

Resistant hypertension

2019-09-23

Genome-wide association analysis of common genetic variants of resistant hypertension.

El Rouby N, McDonough CW et al.

Pharmacogenomics J

Resistant hypertension

2018-09-20

Genome-wide study of resistant hypertension identified from electronic health records.

Dumitrescu L, Ritchie MD et al.

PLoS One

Resistance to antihypertensive treatment in hypertension

2017-01-01