Active: Restless legs syndrome Clear all

GWAS 2024-07-30

Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome.

Akçimen F, Chia R et al.

Ann Neurol

Objective: Restless legs syndrome (RLS) is a neurological condition that causes uncomfortable sensat...

Restless legs syndrome

Replicated

529790

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-05

Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.

Schormair B, Zhao C et al.

Nat Genet

Restless legs syndrome (RLS) affects up to 10% of older adults. Their healthcare is impeded by delay...

Restless legs syndrome

Replicated

27050

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-09

ExomeChip-based rare variant association study in restless legs syndrome.

Tilch E, Schormair B et al.

Sleep Med

Restless legs syndrome (RLS) is a common sleep-related movement disorder in populations of European ...

Restless legs syndrome

9012

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-29

Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs.

Jiang YJ, Fann CS et al.

J Headache Pain

Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contribut...

Restless legs syndrome in migraine

Replicated

1647

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-25

Large genome-wide association study identifies three novel risk variants for restless legs syndrome.

Didriksen M, Nawaz MS et al.

Commun Biol

Restless legs syndrome (RLS) is a common neurological sensorimotor disorder often described as an un...

Restless legs syndrome

Replicated

591833

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-12

Association of genetic variants in migraineurs with and without restless legs syndrome.

Lin GY, Lin YK et al.

Ann Clin Transl Neurol

Objective: Several single-nucleotide polymorphisms (SNPs) are associated with restless legs syndrome...

Restless legs syndrome in migraine without aura

169

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-13

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes.

Wang H, Lane JM et al.

Nat Commun

Excessive daytime sleepiness (EDS) affects 10-20% of the population and is associated with substanti...

Daytime sleepiness

Replicated

486523

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-05

Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.

Jones SE, van Hees VT et al.

Nat Commun

Sleep is an essential human function but its regulation is poorly understood. Using accelerometer da...

Sleep duration

Replicated

91268

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-25

Biological and clinical insights from genetics of insomnia symptoms.

Lane JM, Jones SE et al.

Nat Genet

Insomnia is a common disorder linked with adverse long-term medical and psychiatric outcomes. The un...

Insomnia symptoms (never/rarely vs. sometimes/usually)

Replicated

532369

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-07

A Genome-Wide Association Study Identifies UTRN Gene Polymorphism for Restless Legs Syndrome in a Korean Population.

Cho CH, Choi JH et al.

Psychiatry Investig

Objective: Restless legs syndrome (RLS) is a highly heritable and common neurological sensorimotor d...

Restless legs syndrome

Replicated

3384

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-01

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

Schormair B, Zhao C et al.

Lancet Neurol

Restless legs syndrome is a prevalent chronic neurological disorder with potentially severe mental a...

Restless legs syndrome

Replicated

428534

Participants

N/A

Studies

Details PubMed

GWAS 2017-06-12

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits.

Hammerschlag AR, Stringer S et al.

Nat Genet

Persistent insomnia is among the most frequent complaints in general practice. To identify genetic f...

Insomnia complaints

Replicated

120571

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome.

Akçimen F, Chia R et al.

Ann Neurol

Restless legs syndrome

2024-07-30

Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.

Schormair B, Zhao C et al.

Nat Genet

Restless legs syndrome

2024-06-05

ExomeChip-based rare variant association study in restless legs syndrome.

Tilch E, Schormair B et al.

Sleep Med

Restless legs syndrome

2022-04-09

Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs.

Jiang YJ, Fann CS et al.

J Headache Pain

Restless legs syndrome in migraine

2022-03-29

Large genome-wide association study identifies three novel risk variants for restless legs syndrome.

Didriksen M, Nawaz MS et al.

Commun Biol

Restless legs syndrome

2020-11-25

Association of genetic variants in migraineurs with and without restless legs syndrome.

Lin GY, Lin YK et al.

Ann Clin Transl Neurol

Restless legs syndrome in migraine without aura

2020-09-12

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes.

Wang H, Lane JM et al.

Nat Commun

Daytime sleepiness

2019-08-13

Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.

Jones SE, van Hees VT et al.

Nat Commun

Sleep duration

2019-04-05

Biological and clinical insights from genetics of insomnia symptoms.

Lane JM, Jones SE et al.

Nat Genet

Insomnia symptoms (never/rarely vs. sometimes/usually)

2019-02-25

A Genome-Wide Association Study Identifies UTRN Gene Polymorphism for Restless Legs Syndrome in a Korean Population.

Cho CH, Choi JH et al.

Psychiatry Investig

Restless legs syndrome

2017-11-07

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

Schormair B, Zhao C et al.

Lancet Neurol

Restless legs syndrome

2017-11-01

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits.

Hammerschlag AR, Stringer S et al.

Nat Genet

Insomnia complaints

2017-06-12