Active: Serum uric acid levels Clear all

GWAS 2022-04-26

Weak Association Between Genetic Markers of Hyperuricemia and Cardiorenal Outcomes: Insights From the STANISLAS Study Cohort With a 20-Year Follow-Up.

Kanbay M, Xhaard C et al.

J Am Heart Assoc

Background Hyperuricemia is associated with poor cardiovascular outcomes, although it is uncertain w...

Serum uric acid levels

1573

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-24

Genetics of hyperuricemia and gout: Insights from recent genome-wide association studies and Mendelian randomization studies.

Ko YL

Tzu Chi Med J

Gout is the most common form of inflammatory arthritis in adults. Elevation serum uric acid (SUA) co...

Serum uric acid levels

23067

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-01

Genome-wide meta-analysis revealed several genetic loci associated with serum uric acid levels in Korean population: an analysis of Korea Biobank data.

Park JS, Kim Y et al.

J Hum Genet

The serum uric acid (SUA) level is an important determinant of gout, hypertension, metabolic syndrom...

Serum uric acid levels

60585

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-08

Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals.

Cho SK, Kim B et al.

Sci Rep

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, includi...

Serum uric acid levels

Replicated

10795

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-09

A population-specific low-frequency variant of SLC22A12 (p.W258*) explains nearby genome-wide association signals for serum uric acid concentrations among Koreans.

Im SW, Chae J et al.

PLoS One

Prolonged hyperuricemia is a cause of gout and an independent risk factor for chronic health conditi...

Serum uric acid levels

Replicated

4814

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-16

Refining genome-wide associated loci for serum uric acid in individuals with African ancestry.

Chen G, Shriner D et al.

Hum Mol Genet

Objective: Serum uric acid is the end-product of purine metabolism and at high levels is a risk fact...

Serum uric acid levels

9133

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-14

Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans.

Rivera-Paredez B, Macías-Kauffer L et al.

Nutrients

Risk of hyperuricemia is modified by genetic and environmental factors. Our aim was to identify fact...

Serum uric acid levels

Replicated

4089

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-08

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals.

Nakatochi M, Kanai M et al.

Commun Biol

Gout is a common arthritis caused by elevated serum uric acid (SUA) levels. Here we investigated loc...

Serum uric acid levels

Replicated

223038

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-28

Genome-wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.

Brackman DJ, Yee SW et al.

Clin Pharmacol Ther

Allopurinol, which lowers uric acid (UA) concentration, is increasingly being recognized for its ben...

Response to allopurinol in gout (change in serum uric acid levels)

Replicated

3534

Participants

N/A

Studies

Details PubMed

GWAS 2018-10-01

Genetic contributors to serum uric acid levels in Mexicans and their effect on premature coronary artery disease.

Macias-Kauffer LR, Villamil-Ramírez H et al.

Int J Cardiol

Serum uric acid (SUA) is a heritable trait associated with cardiovascular risk factors and coronary ...

Serum uric acid levels

2153

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-27

Effect of hydrochlorothiazide on serum uric acid concentration: a genome-wide association study.

Ala-Mutka EM, Rimpelä JM et al.

Pharmacogenomics

Aim: To recognize genetic associations of hydrochlorothiazide-induced change in serum uric acid (SUA...

Change in serum uric acid levels in response to thiazide diuretic treatment (hydrochlorothiazide) in hypertension

Replicated

679

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-06

Heritability and Genome-Wide Association Analyses of Serum Uric Acid in Middle and Old-Aged Chinese Twins.

Wang W, Zhang D et al.

Front Endocrinol (Lausanne)

Serum uric acid (SUA), as the end product of purine metabolism, has proven emerging roles in human d...

Serum uric acid levels

278

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Weak Association Between Genetic Markers of Hyperuricemia and Cardiorenal Outcomes: Insights From the STANISLAS Study Cohort With a 20-Year Follow-Up.

Kanbay M, Xhaard C et al.

J Am Heart Assoc

Serum uric acid levels

2022-04-26

Genetics of hyperuricemia and gout: Insights from recent genome-wide association studies and Mendelian randomization studies.

Ko YL

Tzu Chi Med J

Serum uric acid levels

2021-11-24

Genome-wide meta-analysis revealed several genetic loci associated with serum uric acid levels in Korean population: an analysis of Korea Biobank data.

Park JS, Kim Y et al.

J Hum Genet

Serum uric acid levels

2021-11-01

Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals.

Cho SK, Kim B et al.

Sci Rep

Serum uric acid levels

2020-06-08

A population-specific low-frequency variant of SLC22A12 (p.W258*) explains nearby genome-wide association signals for serum uric acid concentrations among Koreans.

Im SW, Chae J et al.

PLoS One

Serum uric acid levels

2020-04-09

Refining genome-wide associated loci for serum uric acid in individuals with African ancestry.

Chen G, Shriner D et al.

Hum Mol Genet

Serum uric acid levels

2019-12-16

Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans.

Rivera-Paredez B, Macías-Kauffer L et al.

Nutrients

Serum uric acid levels

2019-06-14

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals.

Nakatochi M, Kanai M et al.

Commun Biol

Serum uric acid levels

2019-04-08

Genome-wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.

Brackman DJ, Yee SW et al.

Clin Pharmacol Ther

Response to allopurinol in gout (change in serum uric acid levels)

2019-03-28

Genetic contributors to serum uric acid levels in Mexicans and their effect on premature coronary artery disease.

Macias-Kauffer LR, Villamil-Ramírez H et al.

Int J Cardiol

Serum uric acid levels

2018-10-01

Effect of hydrochlorothiazide on serum uric acid concentration: a genome-wide association study.

Ala-Mutka EM, Rimpelä JM et al.

Pharmacogenomics

Change in serum uric acid levels in response to thiazide diuretic treatment (hydrochlorothiazide) in hypertension

2018-03-27

Heritability and Genome-Wide Association Analyses of Serum Uric Acid in Middle and Old-Aged Chinese Twins.

Wang W, Zhang D et al.

Front Endocrinol (Lausanne)

Serum uric acid levels

2018-03-06