Active: Thyroid function Clear all

GWAS 2024-09-13

Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.

Wei Y, Zhen J et al.

Nat Commun

Maintaining normal thyroid function is crucial in pregnancy, yet thyroid dysfunction and the presenc...

Thyroid stimulating hormone levels within normal range in pregnancy

67471

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-01

Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3.

Nolan J, Campbell PJ et al.

Eur J Endocrinol

Objective: Genetic factors underpin the narrow intraindividual variability of thyroid function, alth...

Free thyroxine concentration

Replicated

3936

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-07

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.

Zhou W, Brumpton B et al.

Nat Commun

Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better under...

Thyroid stimulating hormone levels

119715

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-29

Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis.

Brčić L, Barić A et al.

Sci Rep

Thyroid antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) are key markers of Ha...

Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis

405

Participants

N/A

Studies

Details PubMed

GWAS 2018-10-26

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Teumer A, Chaker L et al.

Nat Commun

Thyroid dysfunction is an important public health problem, which affects 10% of the general populati...

Free thyroxine concentration

Replicated

71652

Participants

N/A

Studies

Details PubMed

GWAS 2017-12-07

Genome-Wide Association Study of Male Sexual Orientation.

Sanders AR, Beecham GW et al.

Sci Rep

Family and twin studies suggest that genes play a role in male sexual orientation. We conducted a ge...

Male sexual orientation

2308

Participants

N/A

Studies

Details PubMed

GWAS 2015-03-06

Whole-genome sequence-based analysis of thyroid function.

Taylor PN, Porcu E et al.

Nat Commun

Normal thyroid function is essential for health, but its genetic architecture remains poorly underst...

Thyroid stimulating hormone levels

16335

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-22

Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.

Zhan M, Chen G et al.

Hum Mol Genet

Thyroid-stimulating hormone (TSH) is a sensitive indicator of thyroid function. High and low TSH lev...

Serum thyroid-stimulating hormone levels

Replicated

4581

Participants

N/A

Studies

Details PubMed

GWAS 2014-04-17

A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans.

Kwak SH, Park YJ et al.

Hum Mol Genet

Genetic factors are thought to be an important determinant of thyroid function and autoimmunity. How...

Free thyroxine concentration

Replicated

3618

Participants

N/A

Studies

Details PubMed

GWAS 2013-02-07

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Porcu E, Medici M et al.

PLoS Genet

Thyroid hormone is essential for normal metabolism and development, and overt abnormalities in thyro...

Thyroid hormone levels

26420

Participants

N/A

Studies

Details PubMed

GWAS 2012-04-16

Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.

Rawal R, Teumer A et al.

Hum Mol Genet

Thyroid hormones play key roles in cellular growth, development and metabolism. Although there is a ...

Thyroid function

Replicated

7463

Participants

N/A

Studies

Details PubMed

GWAS 2012-04-06

Novel associations for hypothyroidism include known autoimmune risk loci.

Eriksson N, Tung JY et al.

PLoS One

Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. He...

Hypothyroidism

39282

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.

Wei Y, Zhen J et al.

Nat Commun

Thyroid stimulating hormone levels within normal range in pregnancy

2024-09-13

Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3.

Nolan J, Campbell PJ et al.

Eur J Endocrinol

Free thyroxine concentration

2021-09-01

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.

Zhou W, Brumpton B et al.

Nat Commun

Thyroid stimulating hormone levels

2020-08-07

Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis.

Brčić L, Barić A et al.

Sci Rep

Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis

2019-03-29

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Teumer A, Chaker L et al.

Nat Commun

Free thyroxine concentration

2018-10-26

Genome-Wide Association Study of Male Sexual Orientation.

Sanders AR, Beecham GW et al.

Sci Rep

Male sexual orientation

2017-12-07

Whole-genome sequence-based analysis of thyroid function.

Taylor PN, Porcu E et al.

Nat Commun

Thyroid stimulating hormone levels

2015-03-06

Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.

Zhan M, Chen G et al.

Hum Mol Genet

Serum thyroid-stimulating hormone levels

2014-05-22

A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans.

Kwak SH, Park YJ et al.

Hum Mol Genet

Free thyroxine concentration

2014-04-17

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Porcu E, Medici M et al.

PLoS Genet

Thyroid hormone levels

2013-02-07

Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.

Rawal R, Teumer A et al.

Hum Mol Genet

Thyroid function

2012-04-16

Novel associations for hypothyroidism include known autoimmune risk loci.

Eriksson N, Tung JY et al.

PLoS One

Hypothyroidism

2012-04-06