Active: Type 2 diabetes Clear all

GWAS 2025-11-09

Association of Multiple-trait Polygenic Risk Score with Obesity and Cardiometabolic Diseases in Korean Population.

Jo J, Ha N et al.

Genomics Proteomics Bioinformatics

We conducted a comprehensive genetic investigation of obesity in a cohort of 93,673 Korean individua...

Body mass index

Replicated

484808

Participants

N/A

Studies

Details PubMed

GWAS 2025-08-03

Genetic variants linked to statin-associated Type 2 diabetes mellitus: Findings from the UK Biobank and the All of Us Research Program.

Park YA, Lee DH et al.

Br J Pharmacol

Background and purpose: Statins are widely prescribed for the prevention of cardiovascular disease, ...

Statin-associated type 2 diabetes mellitus

Replicated

110674

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-26

A type 1 diabetes genetic risk score discriminates between type 1 diabetes and type 2 diabetes in a Chinese population.

Hu J, Jiang G et al.

Diabetologia

Aims/hypothesis: We aimed to generate a population-specific type 1 diabetes genetic risk score (GRS)...

Type 1 diabetes

Replicated

137980

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-16

Differential Genetic Architecture of Insulin Resistance (HOMA-IR) Based on Obesity Status: Evidence from a Large-Scale GWAS of Koreans.

Choi JE, Kwon YJ et al.

Curr Issues Mol Biol

Insulin resistance (IR) is a key mechanism underlying type 2 diabetes mellitus and is closely associ...

Homeostasis model assessment of insulin resistance in normal weight

2635

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-05

Genetic risk and polygenic risk score assessment of prediabetes and progression to type 2 diabetes.

Aliyu U, Umlai UI et al.

Diabetes Obes Metab

Aims: To identify susceptibility loci to prediabetes and evaluate the performance of existing polyge...

Prediabetes

10932

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-04

Diversity and longitudinal records: Genetic architecture of disease associations and polygenic risk in the Taiwanese Han population.

Liu TY, Lu HF et al.

Sci Adv

We addressed the underrepresentation of non-European populations in genome-wide association studies ...

Acute vascular insufficiency of intestine (PheCode 441.1)

228734

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-07

Genome-wide approach to study gene-nutrient intake interactions in type 2 diabetes mellitus in a large Korean cohort.

Park JM, Choi JE et al.

Front Nutr

Introduction: A comprehensive understanding of gene-diet interactions is necessary to establish prop...

Type 2 diabetes in vitamin A intake above Dietary Reference Intake

9558

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-05

Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci.

Cole JB, Dahlström EH et al.

J Am Soc Nephrol

Abstract Key Points: Comprehensive genome-wide association study of eGFR in diabetes, accounting for...

eGFR in diabetes mellitus (loose) kidney disease cases (minimal adjustment)

5064

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-05

Genetic architecture and risk prediction of gestational diabetes mellitus in Chinese pregnancies.

Gu Y, Zheng H et al.

Nat Commun

Gestational diabetes mellitus, a heritable metabolic disorder and the most common pregnancy-related ...

Gestational diabetes mellitus

Replicated

97563

Participants

N/A

Studies

Details PubMed

GWAS 2025-04-24

Identifying four obesity axes through integrative multi-omics and imaging analysis.

Odoemelam CS, Naz A et al.

Diabetes

We aimed to identify distinct axes of obesity using advanced magnetic resonance imaging (MRI)-derive...

Peripheral fat axis

25637

Participants

N/A

Studies

Details PubMed

GWAS 2025-04-11

Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.

Petty LE, Chen HH et al.

Nat Commun

Here, we present a multi-omics study of type 2 diabetes and quantitative blood lipid and lipoprotein...

Type 2 diabetes

60975

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-01

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort.

Chebii VJ, Wade AN et al.

Diabetologia

Aims/hypothesis: Glycaemic traits such as high fasting glucose levels and insulin resistance are pos...

Fasting glucose adjusted for BMI

9989

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Association of Multiple-trait Polygenic Risk Score with Obesity and Cardiometabolic Diseases in Korean Population.

Jo J, Ha N et al.

Genomics Proteomics Bioinformatics

Body mass index

2025-11-09

Genetic variants linked to statin-associated Type 2 diabetes mellitus: Findings from the UK Biobank and the All of Us Research Program.

Park YA, Lee DH et al.

Br J Pharmacol

Statin-associated type 2 diabetes mellitus

2025-08-03

A type 1 diabetes genetic risk score discriminates between type 1 diabetes and type 2 diabetes in a Chinese population.

Hu J, Jiang G et al.

Diabetologia

Type 1 diabetes

2025-06-26

Differential Genetic Architecture of Insulin Resistance (HOMA-IR) Based on Obesity Status: Evidence from a Large-Scale GWAS of Koreans.

Choi JE, Kwon YJ et al.

Curr Issues Mol Biol

Homeostasis model assessment of insulin resistance in normal weight

2025-06-16

Genetic risk and polygenic risk score assessment of prediabetes and progression to type 2 diabetes.

Aliyu U, Umlai UI et al.

Diabetes Obes Metab

Prediabetes

2025-06-05

Diversity and longitudinal records: Genetic architecture of disease associations and polygenic risk in the Taiwanese Han population.

Liu TY, Lu HF et al.

Sci Adv

Acute vascular insufficiency of intestine (PheCode 441.1)

2025-06-04

Genome-wide approach to study gene-nutrient intake interactions in type 2 diabetes mellitus in a large Korean cohort.

Park JM, Choi JE et al.

Front Nutr

Type 2 diabetes in vitamin A intake above Dietary Reference Intake

2025-05-07

Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci.

Cole JB, Dahlström EH et al.

J Am Soc Nephrol

eGFR in diabetes mellitus (loose) kidney disease cases (minimal adjustment)

2025-05-05

Genetic architecture and risk prediction of gestational diabetes mellitus in Chinese pregnancies.

Gu Y, Zheng H et al.

Nat Commun

Gestational diabetes mellitus

2025-05-05

Identifying four obesity axes through integrative multi-omics and imaging analysis.

Odoemelam CS, Naz A et al.

Diabetes

Peripheral fat axis

2025-04-24

Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.

Petty LE, Chen HH et al.

Nat Commun

Type 2 diabetes

2025-04-11

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort.

Chebii VJ, Wade AN et al.

Diabetologia

Fasting glucose adjusted for BMI

2025-03-01