Active: Waist-to-hip ratio adjusted for body mass index Clear all

GWAS 2021-06-24

Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL.

Justice AE, Young K et al.

Hum Mol Genet

Central obesity is a leading health concern with a great burden carried by ethnic minority populatio...

Waist-to-hip ratio adjusted for body mass index

Replicated

43560

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-18

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE, Karaderi T et al.

Nat Genet

Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed t...

Waist-to-hip ratio adjusted for BMI (recessive genetic model)

Replicated

476546

Participants

N/A

Studies

Details PubMed

GWAS 2018-04-24

Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans.

Keaton JM, Gao C et al.

Genet Epidemiol

Although type 2 diabetes (T2D) results from metabolic defects in insulin secretion and insulin sensi...

Type 2 diabetes (SNP x SNP interaction, 2df)

6224

Participants

N/A

Studies

Details PubMed

GWAS 2017-04-21

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

Ng MCY, Graff M et al.

PLoS Genet

Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adip...

Waist-to-hip ratio adjusted for body mass index

Replicated

233181

Participants

N/A

Studies

Details PubMed

GWAS 2016-05-19

Investigation of Genetic Variation Underlying Central Obesity amongst South Asians.

Scott WR, Zhang W et al.

PLoS One

South Asians are 1/4 of the world's population and have increased susceptibility to central obesity ...

Waist-to-hip ratio adjusted for body mass index

Replicated

12240

Participants

N/A

Studies

Details PubMed

GWAS 2015-02-12

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin D, Winkler TW et al.

Nature

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic out...

Waist-to-hip ratio adjusted for body mass index

Replicated

223599

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL.

Justice AE, Young K et al.

Hum Mol Genet

Waist-to-hip ratio adjusted for body mass index

2021-06-24

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE, Karaderi T et al.

Nat Genet

Waist-to-hip ratio adjusted for BMI (recessive genetic model)

2019-02-18

Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans.

Keaton JM, Gao C et al.

Genet Epidemiol

Type 2 diabetes (SNP x SNP interaction, 2df)

2018-04-24

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

Ng MCY, Graff M et al.

PLoS Genet

Waist-to-hip ratio adjusted for body mass index

2017-04-21

Investigation of Genetic Variation Underlying Central Obesity amongst South Asians.

Scott WR, Zhang W et al.

PLoS One

Waist-to-hip ratio adjusted for body mass index

2016-05-19

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin D, Winkler TW et al.

Nature

Waist-to-hip ratio adjusted for body mass index

2015-02-12