Active: Aging (Albany NY) Clear all

GWAS 2021-10-29

Predicting physiological aging rates from a range of quantitative traits using machine learning.

Sun ED, Qian Y et al.

Aging (Albany NY)

It is widely thought that individuals age at different rates. A method that measures "physiological ...

Physiological aging rate

6100

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-23

Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia.

Hao Q, Cao M et al.

Aging (Albany NY)

Inherited predispositions to acute lymphoblastic leukemia have been well investigated in pediatric p...

Acute lymphoblastic leukemia

1932

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-24

Generalized correlation coefficient for genome-wide association analysis of cognitive ability in twins.

Mohammadnejad A, Nygaard M et al.

Aging (Albany NY)

Despite a strong genetic background in cognitive function only a limited number of single nucleotide...

Cognitive function (kinship model)

1172

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-07

Identification of cardiovascular health gene variants related to longevity in a Chinese population.

Zhang L, Bai C et al.

Aging (Albany NY)

Cardiovascular disease (CVD) is one of the most important causes of human death, but no attention ha...

Longevity

Replicated

13275

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-01

Genetics of physiological dysregulation: findings from the long life family study using joint models.

Arbeev KG, Bagley O et al.

Aging (Albany NY)

Recently, Mahalanobis distance (DM) was suggested as a statistical measure of physiological dysregul...

Physiological dysregulation (Mahalanobis distance)

4608

Participants

N/A

Studies

Details PubMed

GWAS 2020-03-23

Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease.

Akçimen F, Martins S et al.

Aging (Albany NY)

Machado-Joseph disease (MJD/SCA3) is the most common form of dominantly inherited ataxia worldwide. ...

Machado-Joseph disease (age at onset)

700

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-23

Genome-wide association study of hippocampal atrophy rate in non-demented elders.

Guo Y, Xu W et al.

Aging (Albany NY)

Hippocampal atrophy rate has been correlated with cognitive decline and its genetic modifiers are st...

Hippocampal atrophy rate

602

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-11

Genome-wide association study identifies SIAH3 locus influencing the rate of ventricular enlargement in non-demented elders.

Li X, Chu SG et al.

Aging (Albany NY)

Ventricular enlargement occurs in several neurodegenerative and psychiatric diseases. A large genome...

Rate of ventricular enlargement

507

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-01

Genome-wide association study identifies CBFA2T3 affecting the rate of CSF Aβ42 decline in non-demented elders.

Dou KX, Zhang C et al.

Aging (Albany NY)

Brain amyloid deposition is an early pathological event in Alzheimer's disease (AD), and abnormally ...

Annualised percent change of cerebrospinal fluid AB1-42 levels

321

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-11

Genome-wide association study identifies CD1A associated with rate of increase in plasma neurofilament light in non-demented elders.

Wang ZT, Chen SD et al.

Aging (Albany NY)

As a marker of neuroaxonal injury, neurofilament light (NFL) in blood is robustly elevated in many n...

Change in neurofilament light levels

545

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-01

Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.

Kulminski AM, Huang J et al.

Aging (Albany NY)

A conceptual difficulty in genetics of age-related phenotypes that make individuals vulnerable to di...

Death

33431

Participants

N/A

Studies

Details PubMed

GWAS 2017-12-01

Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.

Pilling LC, Kuo CL et al.

Aging (Albany NY)

We undertook a genome-wide association study (GWAS) of parental longevity in European descent UK Bio...

Parental longevity (combined parental attained age, Martingale residuals)

389166

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Predicting physiological aging rates from a range of quantitative traits using machine learning.

Sun ED, Qian Y et al.

Aging (Albany NY)

Physiological aging rate

2021-10-29

Hao Q, Cao M et al.

Aging (Albany NY)

Acute lymphoblastic leukemia

2021-04-23

Generalized correlation coefficient for genome-wide association analysis of cognitive ability in twins.

Mohammadnejad A, Nygaard M et al.

Aging (Albany NY)

Cognitive function (kinship model)

2020-11-24

Identification of cardiovascular health gene variants related to longevity in a Chinese population.

Zhang L, Bai C et al.

Aging (Albany NY)

Longevity

2020-09-07

Genetics of physiological dysregulation: findings from the long life family study using joint models.

Arbeev KG, Bagley O et al.

Aging (Albany NY)

Physiological dysregulation (Mahalanobis distance)

2020-04-01

Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease.

Akçimen F, Martins S et al.

Aging (Albany NY)

Machado-Joseph disease (age at onset)

2020-03-23

Genome-wide association study of hippocampal atrophy rate in non-demented elders.

Guo Y, Xu W et al.

Aging (Albany NY)

Hippocampal atrophy rate

2019-11-23

Genome-wide association study identifies SIAH3 locus influencing the rate of ventricular enlargement in non-demented elders.

Li X, Chu SG et al.

Aging (Albany NY)

Rate of ventricular enlargement

2019-11-11

Genome-wide association study identifies CBFA2T3 affecting the rate of CSF Aβ42 decline in non-demented elders.

Dou KX, Zhang C et al.

Aging (Albany NY)

Annualised percent change of cerebrospinal fluid AB1-42 levels

2019-08-01

Genome-wide association study identifies CD1A associated with rate of increase in plasma neurofilament light in non-demented elders.

Wang ZT, Chen SD et al.

Aging (Albany NY)

Change in neurofilament light levels

2019-07-11

Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.

Kulminski AM, Huang J et al.

Aging (Albany NY)

Death

2018-03-01

Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.

Pilling LC, Kuo CL et al.

Aging (Albany NY)

Parental longevity (combined parental attained age, Martingale residuals)

2017-12-01