Active: Aging Cell Clear all

GWAS 2024-07-03

SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi-omics research and cohort validation.

Wang S, Yue Y et al.

Aging Cell

Age-related chronic inflammatory lung diseases impose a threat on public health, including idiopathi...

Idiopathic pulmonary fibrosis

744812

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-18

Association of biological age with health outcomes and its modifiable factors.

Liu WS, You J et al.

Aging Cell

Identifying the clinical implications and modifiable and unmodifiable factors of aging requires the ...

Biological age gap

9008

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-25

A genome-wide association study of the frailty index highlights brain pathways in ageing.

Atkins JL, Jylhävä J et al.

Aging Cell

Frailty is a common geriatric syndrome and strongly associated with disability, mortality and hospit...

Frailty index

175226

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-26

Genetic associations for two biological age measures point to distinct aging phenotypes.

Kuo CL, Pilling LC et al.

Aging Cell

Biological age measures outperform chronological age in predicting various aging outcomes, yet littl...

Biological age (BioAge)

Replicated

100228

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-03

Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals.

Liu X, Song Z et al.

Aging Cell

There is growing interest in studying the genetic contributions to longevity, but limited relevant g...

Longevity

11045

Participants

N/A

Studies

Details PubMed

GWAS 2016-06-21

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.

Matteini AM, Tanaka T et al.

Aging Cell

Decline in muscle strength with aging is an important predictor of health trajectory in the elderly....

Hand grip strength

Replicated

33974

Participants

N/A

Studies

Details PubMed

GWAS 2016-06-21

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.

Teumer A, Qi Q et al.

Aging Cell

The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to prom...

Serum levels of protein IGF1

Replicated

30884

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-23

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of PRDM16 gene associated with lean body mass.

Urano T, Shiraki M et al.

Aging Cell

Genetic factors are important for the development of sarcopenia, a geriatric disorder characterized ...

Lean body mass

Replicated

1350

Participants

N/A

Studies

Details PubMed

GWAS 2011-03-21

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Deelen J, Beekman M et al.

Aging Cell

By studying the loci that contribute to human longevity, we aim to identify mechanisms that contribu...

Longevity

Replicated

11731

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi-omics research and cohort validation.

Wang S, Yue Y et al.

Aging Cell

Idiopathic pulmonary fibrosis

2024-07-03

Association of biological age with health outcomes and its modifiable factors.

Liu WS, You J et al.

Aging Cell

Biological age gap

2023-09-18

A genome-wide association study of the frailty index highlights brain pathways in ageing.

Atkins JL, Jylhävä J et al.

Aging Cell

Frailty index

2021-08-25

Genetic associations for two biological age measures point to distinct aging phenotypes.

Kuo CL, Pilling LC et al.

Aging Cell

Biological age (BioAge)

2021-05-26

Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals.

Liu X, Song Z et al.

Aging Cell

Longevity

2021-03-03

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.

Matteini AM, Tanaka T et al.

Aging Cell

Hand grip strength

2016-06-21

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.

Teumer A, Qi Q et al.

Aging Cell

Serum levels of protein IGF1

2016-06-21

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of PRDM16 gene associated with lean body mass.

Urano T, Shiraki M et al.

Aging Cell

Lean body mass

2014-05-23

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Deelen J, Beekman M et al.

Aging Cell

Longevity

2011-03-21