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GWAS 2024-04-15

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.

Yu X, Chen Y et al.

BMC Med

To study the shared genetic structure between autoimmune diseases and B-cell acute lymphoblastic leu...

B-cell lymphoblastic leukemia or adult-onset asthma (pleiotropy)

349240

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-13

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses.

Zhang L, Zhang W et al.

BMC Med

Despite epidemiological evidence associating gallstone disease (GSD) with cardiovascular disease (CV...

Gall stone disease or stroke

1858897

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-19

Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.

Zhang Z, Li H et al.

BMC Med

A large proportion of pulmonary embolism (PE) heritability remains unexplained, particularly among t...

Pulmonary embolism

Replicated

18934

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-11

Identification of genetic variants associated with diabetic kidney disease in multiple Korean cohorts via a genome-wide association study mega-analysis.

Jin H, Kim YA et al.

BMC Med

The pathogenesis of diabetic kidney disease (DKD) is complex, involving metabolic and hemodynamic fa...

Diabetic kidney disease

33879

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-30

A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension.

Xiao X, Li R et al.

BMC Med

Compared with patients who require fewer antihypertensive agents, those with apparent treatment-resi...

Apparent treatment-resistant hypertension

1358

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-01

Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk.

D'Urso S, Arumugam P et al.

BMC Med

Observational epidemiological studies suggest a link between several factors related to ovulation an...

Age at last live birth

203153

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-28

The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study.

Lin C, Sun Z et al.

BMC Med

Circulating levels of amino acids were associated with blood pressure (BP) in observational studies....

Leucine levels

123242

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-31

Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians.

Xiu X, Zhang H et al.

BMC Med

Observational studies have revealed that type 2 diabetes (T2D) is associated with an increased risk ...

Type 2 diabetes or peripheral artery disease (MTAG)

729897

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-23

Genetic predispositions to psychiatric disorders and the risk of COVID-19.

Chen W, Zeng Y et al.

BMC Med

Whether a genetic predisposition to psychiatric disorders is associated with coronavirus disease 201...

Depression

6854

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-13

Your height affects your health: genetic determinants and health-related outcomes in Taiwan.

Chiou JS, Cheng CF et al.

BMC Med

Height is an important anthropometric measurement and is associated with many health-related outcome...

Height

67452

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-22

Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer's disease and Parkinson's disease: a large-scale multi-trait association analysis.

Guo P, Gong W et al.

BMC Med

The current genome-wide association study (GWAS) of Lewy body dementia (LBD) suffers from low power ...

Lewy body dementia (MTAG)

6618

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-13

Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants.

Borges MC, Haycock PC et al.

BMC Med

Despite early interest in the health effects of polyunsaturated fatty acids (PUFA), there is still s...

Circulating docosahexaenoic acid levels

114999

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.

Yu X, Chen Y et al.

BMC Med

B-cell lymphoblastic leukemia or adult-onset asthma (pleiotropy)

2024-04-15

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses.

Zhang L, Zhang W et al.

BMC Med

Gall stone disease or stroke

2023-09-13

Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.

Zhang Z, Li H et al.

BMC Med

Pulmonary embolism

2023-04-19

Identification of genetic variants associated with diabetic kidney disease in multiple Korean cohorts via a genome-wide association study mega-analysis.

Jin H, Kim YA et al.

BMC Med

Diabetic kidney disease

2023-01-11

A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension.

Xiao X, Li R et al.

BMC Med

Apparent treatment-resistant hypertension

2022-11-30

Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk.

D'Urso S, Arumugam P et al.

BMC Med

Age at last live birth

2022-11-01

The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study.

Lin C, Sun Z et al.

BMC Med

Leucine levels

2022-10-28

Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians.

Xiu X, Zhang H et al.

BMC Med

Type 2 diabetes or peripheral artery disease (MTAG)

2022-08-31

Genetic predispositions to psychiatric disorders and the risk of COVID-19.

Chen W, Zeng Y et al.

BMC Med

Depression

2022-08-23

Your height affects your health: genetic determinants and health-related outcomes in Taiwan.

Chiou JS, Cheng CF et al.

BMC Med

Height

2022-07-13

Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer's disease and Parkinson's disease: a large-scale multi-trait association analysis.

Guo P, Gong W et al.

BMC Med

Lewy body dementia (MTAG)

2022-06-22

Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants.

Borges MC, Haycock PC et al.

BMC Med

Circulating docosahexaenoic acid levels

2022-06-13