Active: Cancer Clear all

GWAS 2024-12-05

A genome-wide association study identifies eight loci associated with intraductal papillary mucinous neoplasm progression toward malignancy.

Gentiluomo M, Corradi C et al.

Cancer

Intraductal papillary mucinous neoplasms (IPMNs) are precursors to pancreatic cancer, but not all IP...

Intraductal papillary mucinous neoplasm (adjusted for cyst)

338

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-19

Clinical and genetic risk factors for radiation-associated ototoxicity: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort.

Trendowski MR, Baedke JL et al.

Cancer

Cranial radiation therapy (CRT) is associated with ototoxicity, which manifests as hearing loss and ...

Tinnitus in cranial radiation therapy-treated pediatric cancer survivors

Replicated

2943

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-05

A prospective trial of abiraterone acetate plus prednisone in Black and White men with metastatic castrate-resistant prostate cancer.

George DJ, Halabi S et al.

Cancer

Retrospective analyses of randomized trials suggest that Black men with metastatic castration-resist...

Prostate-specific antigen progression (time to event) in metastatic castration-resistant prostate cancer

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-13

Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort.

Richard MA, Brown AL et al.

Cancer

Treatment characteristics such as cranial radiation therapy (CRT) do not fully explain adiposity ris...

BMI in adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation

Replicated

1222

Participants

N/A

Studies

Details PubMed

GWAS 2017-12-19

Bone mineral density in children with acute lymphoblastic leukemia.

Inaba H, Cao X et al.

Cancer

Children with acute lymphoblastic leukemia (ALL) can develop reduced bone mineral density (BMD). How...

Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia

296

Participants

N/A

Studies

Details PubMed

GWAS 2017-06-29

Genome-wide association analysis identifies a GLUL haplotype for familial hepatitis B virus-related hepatocellular carcinoma.

Lin YY, Yu MW et al.

Cancer

A family history of liver cancer increases the risk of developing hepatocellular carcinoma (HCC) by ...

Familial hepatitis B virus-related hepatocellular carcinoma

278

Participants

N/A

Studies

Details PubMed

GWAS 2015-05-11

Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort.

Wilson CL, Liu W et al.

Cancer

The objective of this study was to identify treatment and genetic factors associated with obesity am...

Obesity in adult survivors of childhood cancer exposed to cranial radiation

776

Participants

N/A

Studies

Details PubMed

GWAS 2012-01-03

Identification of novel germline polymorphisms governing capecitabine sensitivity.

O'Donnell PH, Stark AL et al.

Cancer

Capecitabine, an oral 5-fluorouracil (5-FU) prodrug, is widely used in the treatment of breast, colo...

Capecitabine sensitivity

503

Participants

N/A

Studies

Details PubMed

GWAS 2011-10-21

Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients.

Won HH, Lee J et al.

Cancer

To identify potential genetic markers for severe oxaliplatin-induced chronic peripheral neuropathy (...

Response to platinum-based agents

Replicated

343

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study identifies eight loci associated with intraductal papillary mucinous neoplasm progression toward malignancy.

Gentiluomo M, Corradi C et al.

Cancer

Intraductal papillary mucinous neoplasm (adjusted for cyst)

2024-12-05

Clinical and genetic risk factors for radiation-associated ototoxicity: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort.

Trendowski MR, Baedke JL et al.

Cancer

Tinnitus in cranial radiation therapy-treated pediatric cancer survivors

2021-07-19

A prospective trial of abiraterone acetate plus prednisone in Black and White men with metastatic castrate-resistant prostate cancer.

George DJ, Halabi S et al.

Cancer

Prostate-specific antigen progression (time to event) in metastatic castration-resistant prostate cancer

2021-05-05

Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort.

Richard MA, Brown AL et al.

Cancer

BMI in adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation

2020-10-13

Bone mineral density in children with acute lymphoblastic leukemia.

Inaba H, Cao X et al.

Cancer

Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia

2017-12-19

Genome-wide association analysis identifies a GLUL haplotype for familial hepatitis B virus-related hepatocellular carcinoma.

Lin YY, Yu MW et al.

Cancer

Familial hepatitis B virus-related hepatocellular carcinoma

2017-06-29

Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort.

Wilson CL, Liu W et al.

Cancer

Obesity in adult survivors of childhood cancer exposed to cranial radiation

2015-05-11

Identification of novel germline polymorphisms governing capecitabine sensitivity.

O'Donnell PH, Stark AL et al.

Cancer

Capecitabine sensitivity

2012-01-03

Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients.

Won HH, Lee J et al.

Cancer

Response to platinum-based agents

2011-10-21