Active: Cancer Res Clear all

GWAS 2024-06-04

Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants that Confer Risk for Breast Cancer.

Sun X, Verma SP et al.

Cancer Res

Breast cancer includes several subtypes with distinct characteristic biological, pathologic, and cli...

Breast cancer subtype (luminal B-like vs luminal A-like)

73129

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-24

Genome-wide association analyses identify CATSPERE as a mediator of colorectal cancer susceptibility and progression.

Meng Y, Du M et al.

Cancer Res

Genome-wide association studies (GWAS) have revealed numerous genetic loci associated with colorecta...

Colorectal cancer

Replicated

15698

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-23

Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors.

Hong W, Li A et al.

Cancer Res

Clonal hematopoiesis (CH) is a phenomenon caused by expansion of white blood cells descended from a ...

Number of clonal hematopoiesis mutations

1958

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-11

Smoking modifies pancreatic cancer risk loci on 2q21.3.

Mocci E, Kundu P et al.

Cancer Res

Germline variation and smoking are independently associated with pancreatic ductal adenocarcinoma (P...

Pancreatic ductal adenocarcinoma x smoking interaction

19711

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-08

A large-scale association study detects novel rare variants, risk genes, functional elements, and polygenic architecture of prostate cancer susceptibility.

Emami NC, Cavazos TB et al.

Cancer Res

To identify rare variants associated with prostate cancer susceptibility and better characterize the...

Prostate cancer

208253

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-10

A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck.

Shete S, Liu H et al.

Cancer Res

To identify genetic variants for risk of squamous cell carcinoma of the head and neck (SCCHN), we co...

Oral cavity cancer

Replicated

10924

Participants

N/A

Studies

Details PubMed

GWAS 2016-10-10

Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy.

Ingle JN, Xie F et al.

Cancer Res

Genetic risks in breast cancer remain only partly understood. Here, we report the results of a genom...

Breast cancer-free interval (treatment with aromatase inhibitor)

4658

Participants

N/A

Studies

Details PubMed

GWAS 2016-08-03

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.

Patel YM, Park SL et al.

Cancer Res

Metabolism of nicotine by cytochrome P450 2A6 (CYP2A6) is a suspected determinant of smoking dose an...

Nicotine metabolite ratio in current smokers

2239

Participants

N/A

Studies

Details PubMed

GWAS 2016-04-20

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

Fehringer G, Kraft P et al.

Cancer Res

Identifying genetic variants with pleiotropic associations can uncover common pathways influencing m...

Cancer (pleiotropy)

123671

Participants

N/A

Studies

Details PubMed

GWAS 2016-03-29

Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3.

Wang M, Li Z et al.

Cancer Res

Genome-wide association studies (GWAS) of bladder cancer have identified a number of susceptibility ...

Bladder cancer

Replicated

8051

Participants

N/A

Studies

Details PubMed

GWAS 2015-07-16

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.

Leng S, Wu G et al.

Cancer Res

O(6)-Methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that protects cells from carc...

MGMT methylation in smokers

Replicated

1593

Participants

N/A

Studies

Details PubMed

GWAS 2013-05-23

Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers.

Wu X, Wang L et al.

Cancer Res

To identify the genetic factors that influence overall survival in never smokers who have non-small ...

Non-small cell lung cancer (survival)

Replicated

1876

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants that Confer Risk for Breast Cancer.

Sun X, Verma SP et al.

Cancer Res

Breast cancer subtype (luminal B-like vs luminal A-like)

2024-06-04

Genome-wide association analyses identify CATSPERE as a mediator of colorectal cancer susceptibility and progression.

Meng Y, Du M et al.

Cancer Res

Colorectal cancer

2022-01-24

Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors.

Hong W, Li A et al.

Cancer Res

Number of clonal hematopoiesis mutations

2021-11-23

Smoking modifies pancreatic cancer risk loci on 2q21.3.

Mocci E, Kundu P et al.

Cancer Res

Pancreatic ductal adenocarcinoma x smoking interaction

2021-02-11

A large-scale association study detects novel rare variants, risk genes, functional elements, and polygenic architecture of prostate cancer susceptibility.

Emami NC, Cavazos TB et al.

Cancer Res

Prostate cancer

2020-12-08

A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck.

Shete S, Liu H et al.

Cancer Res

Oral cavity cancer

2020-04-10

Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy.

Ingle JN, Xie F et al.

Cancer Res

Breast cancer-free interval (treatment with aromatase inhibitor)

2016-10-10

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk.

Patel YM, Park SL et al.

Cancer Res

Nicotine metabolite ratio in current smokers

2016-08-03

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

Fehringer G, Kraft P et al.

Cancer Res

Cancer (pleiotropy)

2016-04-20

Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3.

Wang M, Li Z et al.

Cancer Res

Bladder cancer

2016-03-29

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.

Leng S, Wu G et al.

Cancer Res

MGMT methylation in smokers

2015-07-16

Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers.

Wu X, Wang L et al.

Cancer Res

Non-small cell lung cancer (survival)

2013-05-23