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GWAS 2025-08-19

Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene.

Sonehara K, Watanabe R et al.

Cell Genom

Psoriasis vulgaris (PsV) is an immune-mediated inflammatory skin disorder with complex genetic archi...

Psoriasis vulgaris

5383

Participants

N/A

Studies

Details PubMed

GWAS 2025-04-11

Improved genetic discovery and fine-mapping resolution through multivariate latent factor analysis of high-dimensional traits.

Zhou F, Astle WJ et al.

Cell Genom

Genome-wide association studies (GWASs) of high-dimensional traits, such as blood cell or metabolic ...

Blood cell traits latent factor 1 (white cell)

18310

Participants

N/A

Studies

Details PubMed

GWAS 2024-10-01

A genome-wide association study of neonatal metabolites.

He Q, Liu H et al.

Cell Genom

Genetic factors significantly influence the concentration of metabolites in adults. Nevertheless, th...

Neonatal citrulline levels (maternal genotype effect)

Replicated

27785

Participants

N/A

Studies

Details PubMed

GWAS 2024-08-09

Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity.

Tervi A, Ramste M et al.

Cell Genom

Raynaud's syndrome is a dysautonomia where exposure to cold causes vasoconstriction and hypoxia, par...

Raynaud's syndrome

412232

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-01

Genome-wide association study of the common retinal disorder epiretinal membrane: Significant risk loci in each of three American populations.

Gelernter J, Levey DF et al.

Cell Genom

Epiretinal membrane (ERM) is a common retinal condition characterized by the presence of fibrocellul...

Epiretinal membrane

445426

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-20

Genetic associations with ratios between protein levels detect new pQTLs and reveal protein-protein interactions.

Suhre K

Cell Genom

Protein quantitative trait loci (pQTLs) are an invaluable source of information for drug target deve...

METAP2/USP8 protein level ratio

43509

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-20

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.

Hughes O, Bentley AR et al.

Cell Genom

Chronic kidney disease is a leading cause of death and disability globally and impacts individuals o...

Estimated glomerular filtration rate

145732

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-13

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.

Borbye-Lorenzen N, Zhu Z et al.

Cell Genom

Complement components have been linked to schizophrenia and autoimmune disorders. We examined the as...

Neonatal circulating Complement Component 3 (C3) protein concentration

68768

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-13

Polymorphic short tandem repeats make widespread contributions to blood and serum traits.

Margoliash J, Fuchs S et al.

Cell Genom

Short tandem repeats (STRs) are genomic regions consisting of repeated sequences of 1-6 bp in succes...

Platelet distribution width (short tandem repeats)

15065

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-16

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.

Chen CY, Chen TT et al.

Cell Genom

Genome-wide association studies (GWASs) have identified tens of thousands of genetic loci associated...

Hemoglobin

92615

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-20

Genotyping and population characteristics of the China Kadoorie Biobank.

Walters RG, Millwood IY et al.

Cell Genom

The China Kadoorie Biobank (CKB) is a population-based prospective cohort of >512,000 adults recr...

ICD10 A09: Infectious gastroenteritis and colitis, unspecified

76516

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-23

Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy.

Kleeman SO, Thakir TM et al.

Cell Genom

Cystatin C (CyC), a secreted cysteine protease inhibitor, has unclear biological functions. Many pat...

Cystatin C production

381764

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene.

Sonehara K, Watanabe R et al.

Cell Genom

Psoriasis vulgaris

2025-08-19

Improved genetic discovery and fine-mapping resolution through multivariate latent factor analysis of high-dimensional traits.

Zhou F, Astle WJ et al.

Cell Genom

Blood cell traits latent factor 1 (white cell)

2025-04-11

A genome-wide association study of neonatal metabolites.

He Q, Liu H et al.

Cell Genom

Neonatal citrulline levels (maternal genotype effect)

2024-10-01

Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity.

Tervi A, Ramste M et al.

Cell Genom

Raynaud's syndrome

2024-08-09

Genome-wide association study of the common retinal disorder epiretinal membrane: Significant risk loci in each of three American populations.

Gelernter J, Levey DF et al.

Cell Genom

Epiretinal membrane

2024-06-01

Genetic associations with ratios between protein levels detect new pQTLs and reveal protein-protein interactions.

Suhre K

Cell Genom

METAP2/USP8 protein level ratio

2024-02-20

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.

Hughes O, Bentley AR et al.

Cell Genom

Estimated glomerular filtration rate

2023-12-20

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.

Borbye-Lorenzen N, Zhu Z et al.

Cell Genom

Neonatal circulating Complement Component 3 (C3) protein concentration

2023-12-13

Polymorphic short tandem repeats make widespread contributions to blood and serum traits.

Margoliash J, Fuchs S et al.

Cell Genom

Platelet distribution width (short tandem repeats)

2023-12-13

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.

Chen CY, Chen TT et al.

Cell Genom

Hemoglobin

2023-11-16

Genotyping and population characteristics of the China Kadoorie Biobank.

Walters RG, Millwood IY et al.

Cell Genom

ICD10 A09: Infectious gastroenteritis and colitis, unspecified

2023-07-20

Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy.

Kleeman SO, Thakir TM et al.

Cell Genom

Cystatin C production

2023-06-23