Active: Circ Res Clear all

GWAS 2022-06-14

Genome Wide Association Studies of Variant-by-Thiazide Interaction on Lipids Identifies a Novel Low-Density Lipoprotein Cholesterol Locus.

Downie CG, Highland HM et al.

Circ Res

No abstract available Keywords: cholesterol; cholesterol, LDL; diuretics; pharmacogenetics; thiazide...

LDL cholesterol x thiazide diuretic use interaction

394444

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-12

Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells.

Aherrahrou R, Guo L et al.

Circ Res

Rationale: Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Rece...

Aortic vascular smooth muscle cell calcification in response to osteogenic stimuli

151

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-01

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome.

Mola-Caminal M, Carrera C et al.

Circ Res

Rationale: Ischemic stroke is among the leading causes of adult disability. Part of the variability ...

3-month functional outcome in ischaemic stroke (modified Rankin score)

Replicated

3016

Participants

N/A

Studies

Details PubMed

GWAS 2017-12-06

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.

van der Harst P, Verweij N

Circ Res

Rationale: Coronary artery disease (CAD) is a complex phenotype driven by genetic and environmental ...

Coronary artery disease

Replicated

547261

Participants

N/A

Studies

Details PubMed

GWAS 2016-11-29

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Jones GT, Tromp G et al.

Circ Res

Rationale: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental ...

Abdominal aortic aneurysm

Replicated

117970

Participants

N/A

Studies

Details PubMed

GWAS 2011-07-14

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.

Debette S, Visvikis-Siest S et al.

Circ Res

Rationale: Vascular endothelial growth factor (VEGF) affects angiogenesis, atherosclerosis, and canc...

Vascular endothelial growth factor levels

Replicated

5254

Participants

N/A

Studies

Details PubMed

GWAS 2011-01-06

Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families.

Arnett DK, Meyers KJ et al.

Circ Res

Rationale: Left ventricular (LV) mass and related phenotypes are heritable, important predictors of ...

Cardiac muscle measurement

Replicated

3563

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome Wide Association Studies of Variant-by-Thiazide Interaction on Lipids Identifies a Novel Low-Density Lipoprotein Cholesterol Locus.

Downie CG, Highland HM et al.

Circ Res

LDL cholesterol x thiazide diuretic use interaction

2022-06-14

Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells.

Aherrahrou R, Guo L et al.

Circ Res

Aortic vascular smooth muscle cell calcification in response to osteogenic stimuli

2020-10-12

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome.

Mola-Caminal M, Carrera C et al.

Circ Res

3-month functional outcome in ischaemic stroke (modified Rankin score)

2019-01-01

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.

van der Harst P, Verweij N

Circ Res

Coronary artery disease

2017-12-06

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Jones GT, Tromp G et al.

Circ Res

Abdominal aortic aneurysm

2016-11-29

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.

Debette S, Visvikis-Siest S et al.

Circ Res

Vascular endothelial growth factor levels

2011-07-14

Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families.

Arnett DK, Meyers KJ et al.

Circ Res

Cardiac muscle measurement

2011-01-06