Active: Diabetes Clear all

GWAS 2025-04-24

Identifying four obesity axes through integrative multi-omics and imaging analysis.

Odoemelam CS, Naz A et al.

Diabetes

We aimed to identify distinct axes of obesity using advanced magnetic resonance imaging (MRI)-derive...

Peripheral fat axis

25637

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-18

Genetics of C-peptide and Age at Diagnosis in Type 1 Diabetes.

Roshandel D, Spiliopoulou A et al.

Diabetes

Identified genetic loci for C-peptide and type 1 diabetes (T1D) age at diagnosis (AAD) explain only ...

C-peptide levels in type I diabetes

7252

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-13

Characterizing common and rare variations in non-traditional glycemic biomarkers using multivariate approaches on multi-ancestry ARIC study.

Ray D, Loomis SJ et al.

Diabetes

Genetic studies of nontraditional glycemic biomarkers, glycated albumin and fructosamine, can shed l...

Fructosamine levels and percent glycated albumin (multivariate analysis)

9363

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-15

Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits.

Westerman KE, Walker ME et al.

Diabetes

Few studies have demonstrated reproducible gene-diet interactions (GDIs) impacting metabolic disease...

HbA1c levels x carbohydrate intake interaction (2df)

29783

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-23

Genome-wide Association Study Identifies Genetic Loci Associated with Fat Cell Number and Overlap with Genetic Risk Loci For Type 2 Diabetes.

Kulyté A, Aman A et al.

Diabetes

Interindividual differences in generation of new fat cells determine body fat and type 2 diabetes ri...

Abdominal fat cell number

896

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-03

Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.

O'Connor MJ, Schroeder P et al.

Diabetes

Most genome-wide association studies (GWAS) of complex traits are performed using models with additi...

Type 2 diabetes

Replicated

419559

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-09

An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.

Riveros-Mckay F, Roberts D et al.

Diabetes

Fructosamine is a measure of short-term glycemic control, which has been suggested as a useful compl...

Fructosamine levels

Replicated

20731

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-05

Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism.

Li-Gao R, Hughes DA et al.

Diabetes

Humans spend the greater part of the day in a postprandial state. However, the genetic basis of post...

Postprandial phosphatidylcholine and other cholines

4348

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-12

Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.

Martin S, Cule M et al.

Diabetes

To understand the causal role of adiposity and ectopic fat in type 2 diabetes and cardiometabolic di...

Body fat percentage

442278

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-21

The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium.

Srinivasan S, Chen L et al.

Diabetes

The prevalence of type 2 diabetes in youth has increased substantially, yet the genetic underpinning...

Childhood onset type 2 diabetes

9067

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-11

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity.

Yaghootkar H, Zhang Y et al.

Diabetes

Leptin influences food intake by informing the brain about the status of body fat stores. Rare LEP m...

circulating leptin levels

56802

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-03

Phenotypic and Genetic Characterization of Lower LDL-C and Increased Type-2 Diabetes Risk in the UK Biobank.

Klimentidis YC, Arora A et al.

Diabetes

Although hyperlipidemia is traditionally considered a risk factor for type 2 diabetes (T2D), evidenc...

Low density lipoprotein cholesterol levels

431167

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Identifying four obesity axes through integrative multi-omics and imaging analysis.

Odoemelam CS, Naz A et al.

Diabetes

Peripheral fat axis

2025-04-24

Genetics of C-peptide and Age at Diagnosis in Type 1 Diabetes.

Roshandel D, Spiliopoulou A et al.

Diabetes

C-peptide levels in type I diabetes

2024-11-18

Characterizing common and rare variations in non-traditional glycemic biomarkers using multivariate approaches on multi-ancestry ARIC study.

Ray D, Loomis SJ et al.

Diabetes

Fructosamine levels and percent glycated albumin (multivariate analysis)

2024-06-13

Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits.

Westerman KE, Walker ME et al.

Diabetes

HbA1c levels x carbohydrate intake interaction (2df)

2023-02-15

Genome-wide Association Study Identifies Genetic Loci Associated with Fat Cell Number and Overlap with Genetic Risk Loci For Type 2 Diabetes.

Kulyté A, Aman A et al.

Diabetes

Abdominal fat cell number

2022-03-23

Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.

O'Connor MJ, Schroeder P et al.

Diabetes

Type 2 diabetes

2021-12-03

An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.

Riveros-Mckay F, Roberts D et al.

Diabetes

Fructosamine levels

2021-11-09

Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism.

Li-Gao R, Hughes DA et al.

Diabetes

Postprandial phosphatidylcholine and other cholines

2021-10-05

Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.

Martin S, Cule M et al.

Diabetes

Body fat percentage

2021-05-12

The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium.

Srinivasan S, Chen L et al.

Diabetes

Childhood onset type 2 diabetes

2021-01-21

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity.

Yaghootkar H, Zhang Y et al.

Diabetes

circulating leptin levels

2020-09-11

Phenotypic and Genetic Characterization of Lower LDL-C and Increased Type-2 Diabetes Risk in the UK Biobank.

Klimentidis YC, Arora A et al.

Diabetes

Low density lipoprotein cholesterol levels

2020-06-03