Active: Front Cardiovasc Med Clear all

GWAS 2023-06-20

Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma.

Tantawy M, Yang G et al.

Front Cardiovasc Med

Proteasome inhibitor Carfilzomib (CFZ) is effective in treating patients with refractory or relapsed...

Cardiovascular adverse events in carfilzomib-treated multiple myeloma

228

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-22

Genome-wide association study for vascular aging highlights pathways shared with cardiovascular traits in Koreans.

Ahn J, Jeong H et al.

Front Cardiovasc Med

Vascular aging plays a pivotal role in the morbidity and mortality of older people. Reactive hyperem...

Vascular endothelial function

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-06

Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population.

Sethi A, Taylor DL et al.

Front Cardiovasc Med

Calcification of large arteries is a high-risk factor in the development of cardiovascular diseases,...

Abdominal aortic calcification levels

Replicated

72989

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-08

A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype.

Cárcel-Márquez J, Muiño E et al.

Front Cardiovasc Med

Occult atrial fibrillation (AF) is one of the major causes of embolic stroke of undetermined source ...

Cardioembolic stroke (MTAG)

362661

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-31

Genetic Determinants of Visit-to-Visit Lipid Variability: Genome-Wide Association Study in Statin-Naïve Korean Population.

Park JB, Shin E et al.

Front Cardiovasc Med

Background and aim: There is a growing evidence that fluctuation in lipid profiles is important in c...

Low density lipoprotein cholesterol variability

Replicated

5373

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-14

Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population.

de Haan A, Ahmadizar F et al.

Front Cardiovasc Med

Serum calciprotein particle maturation time (T50), a measure of vascular calcification propensity, i...

Serum calciprotein particle maturation time (T50)

2739

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-11

Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases.

Zhang F, Cao H et al.

Front Cardiovasc Med

Major depressive disorder (MDD) is phenotypically associated with cardiovascular diseases (CVD). We ...

Major depressive disorder or stroke (pleiotropy)

927055

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-16

Sortilin as a Biomarker for Cardiovascular Disease Revisited.

Møller PL, Rohde PD et al.

Front Cardiovasc Med

Genetic variants in the genomic region containing SORT1 (encoding the protein sortilin) are strongly...

Sortilin levels (ELISA)

1173

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-20

Genome-Wide Association Analysis for Severity of Coronary Artery Disease Using the Gensini Scoring System.

Zeller T, Seiffert M et al.

Front Cardiovasc Med

Coronary artery disease (CAD) has a complex etiology involving numerous environmental and genetic fa...

Coronary artery disease severity measurement

Replicated

7214

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma.

Tantawy M, Yang G et al.

Front Cardiovasc Med

Cardiovascular adverse events in carfilzomib-treated multiple myeloma

2023-06-20

Genome-wide association study for vascular aging highlights pathways shared with cardiovascular traits in Koreans.

Ahn J, Jeong H et al.

Front Cardiovasc Med

Vascular endothelial function

2022-12-22

Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population.

Sethi A, Taylor DL et al.

Front Cardiovasc Med

Abdominal aortic calcification levels

2022-10-06

A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype.

Cárcel-Márquez J, Muiño E et al.

Front Cardiovasc Med

Cardioembolic stroke (MTAG)

2022-07-08

Genetic Determinants of Visit-to-Visit Lipid Variability: Genome-Wide Association Study in Statin-Naïve Korean Population.

Park JB, Shin E et al.

Front Cardiovasc Med

Low density lipoprotein cholesterol variability

2022-01-31

Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population.

de Haan A, Ahmadizar F et al.

Front Cardiovasc Med

Serum calciprotein particle maturation time (T50)

2022-01-14

Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases.

Zhang F, Cao H et al.

Front Cardiovasc Med

Major depressive disorder or stroke (pleiotropy)

2021-11-11

Sortilin as a Biomarker for Cardiovascular Disease Revisited.

Møller PL, Rohde PD et al.

Front Cardiovasc Med

Sortilin levels (ELISA)

2021-04-16

Genome-Wide Association Analysis for Severity of Coronary Artery Disease Using the Gensini Scoring System.

Zeller T, Seiffert M et al.

Front Cardiovasc Med

Coronary artery disease severity measurement

2017-09-20