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GWAS 2025-10-11

Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.

Dack K, Ludwig KU et al.

Hum Mol Genet

Several genome wide association studies (GWASs) of orofacial cleft have been conducted. However only...

Orofacial clefts

10181

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-08

Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.

Byun J, Han Y et al.

Hum Mol Genet

Despite lung cancer affecting all races and ethnicities, disparities are observed in incidence and m...

Lung adenocarcinoma

5274

Participants

N/A

Studies

Details PubMed

GWAS 2025-02-10

Genetic analysis of elevated levels of creatinine and cystatin C biomarkers reveals novel genetic loci associated with kidney function.

D'Antonio M, Arthur TD et al.

Hum Mol Genet

The rising prevalence of chronic kidney disease (CKD), affecting an estimated 37 million adults in t...

Estimated glomerular filtration rate based on creatinine (2009 formula) in top 10% of individuals by creatinine levels

40170

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-22

The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture.

Faber BG, Frysz M et al.

Hum Mol Genet

Objectives: Hip shape is thought to be an important causal risk factor for hip osteoarthritis and fr...

Hip shape mode 1

43485

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-13

Genetic analysis implicates ERAP1 and HLA as risk factors for severe Puumala virus infection.

Haapaniemi H, Strausz S et al.

Hum Mol Genet

Puumala virus (PUUV) infections can cause severe illnesses such as Hemorrhagic Fever with Renal Synd...

Hemorrhagic fever with renal syndrome

500402

Participants

N/A

Studies

Details PubMed

GWAS 2024-07-09

Joint models reveal genetic architecture of pubertal stage transitions and their association with BMI in admixed Chilean population.

Vicuña L, Barrientos E et al.

Hum Mol Genet

Early or late pubertal onset can lead to disease in adulthood, including cancer, obesity, type 2 dia...

Tanner 2 to Tanner 3 pubertal stage transition (survival model)

346

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-15

Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.

Jiang MZ, Gaynor SM et al.

Hum Mol Genet

Inflammation biomarkers can provide valuable insight into the role of inflammatory processes in many...

CD40 levels

2381

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-14

Novel signals and polygenic score for height are associated with pubertal growth traits in Southwestern American Indians.

Ramírez-Luzuriaga MJ, Kobes S et al.

Hum Mol Genet

Most genetic variants associated with adult height have been identified through large genome-wide as...

Adolescent growth

787

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-07

A multi-ancestry genome-wide association study in type 1 diabetes.

Michalek DA, Tern C et al.

Hum Mol Genet

Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of the pancreatic β-cells. Geno...

Type 1 diabetes

308

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-02

Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration.

Kwong A, Zawistowski M et al.

Hum Mol Genet

Genome-wide association studies have contributed extensively to the discovery of disease-associated ...

Age-related macular degeneration

4787

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-03

Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibility.

Liao SY, Jacobson S et al.

Hum Mol Genet

Sarcoidosis is a complex systemic disease. Our study aimed to (1) identify novel alleles associated ...

Sarcoidosis

2599

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-29

Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration.

Scammell BH, Tchio C et al.

Hum Mol Genet

Both short (≤6 h per night) and long sleep duration (≥9 h per night) are associated with increased r...

Sleep duration

483235

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.

Dack K, Ludwig KU et al.

Hum Mol Genet

Orofacial clefts

2025-10-11

Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.

Byun J, Han Y et al.

Hum Mol Genet

Lung adenocarcinoma

2025-05-08

Genetic analysis of elevated levels of creatinine and cystatin C biomarkers reveals novel genetic loci associated with kidney function.

D'Antonio M, Arthur TD et al.

Hum Mol Genet

Estimated glomerular filtration rate based on creatinine (2009 formula) in top 10% of individuals by creatinine levels

2025-02-10

The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture.

Faber BG, Frysz M et al.

Hum Mol Genet

Hip shape mode 1

2024-11-22

Genetic analysis implicates ERAP1 and HLA as risk factors for severe Puumala virus infection.

Haapaniemi H, Strausz S et al.

Hum Mol Genet

Hemorrhagic fever with renal syndrome

2024-11-13

Joint models reveal genetic architecture of pubertal stage transitions and their association with BMI in admixed Chilean population.

Vicuña L, Barrientos E et al.

Hum Mol Genet

Tanner 2 to Tanner 3 pubertal stage transition (survival model)

2024-07-09

Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.

Jiang MZ, Gaynor SM et al.

Hum Mol Genet

CD40 levels

2024-05-15

Novel signals and polygenic score for height are associated with pubertal growth traits in Southwestern American Indians.

Ramírez-Luzuriaga MJ, Kobes S et al.

Hum Mol Genet

Adolescent growth

2024-03-14

A multi-ancestry genome-wide association study in type 1 diabetes.

Michalek DA, Tern C et al.

Hum Mol Genet

Type 1 diabetes

2024-03-07

Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration.

Kwong A, Zawistowski M et al.

Hum Mol Genet

Age-related macular degeneration

2023-11-02

Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibility.

Liao SY, Jacobson S et al.

Hum Mol Genet

Sarcoidosis

2023-07-03

Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration.

Scammell BH, Tchio C et al.

Hum Mol Genet

Sleep duration

2023-06-29