Active: J Alzheimers Dis Clear all

GWAS 2024-01-31

Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.

Dai Y, Hsu YC et al.

J Alzheimers Dis

The progressive cognitive decline, an integral component of Alzheimer's disease (AD), unfolds in tan...

Accelerated cognitive decline

1064

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-09

Genome-Wide Association Study of Incident Dementia in a Community-Based Sample of Older Subjects.

Harper JD, Fan KH et al.

J Alzheimers Dis

Alzheimer's disease (AD) is a complex disease influenced by the environment and genetics; however, m...

Alzheimer's disease

2592

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-18

Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study.

Kang S, Gim J et al.

J Alzheimers Dis

The present study reports two novel genome-wide significant loci for late-onset Alzheimer's disease ...

Late-onset Alzheimer's disease

Replicated

4247

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-10

Genome-Wide Association Study of Brain Alzheimer's Disease-Related Metabolic Decline as Measured by [18F] FDG-PET Imaging.

Wang RZ, Yang YX et al.

J Alzheimers Dis

Hypometabolism detected by fluorodeoxyglucose F18 positron emission tomography ([18F] FDG PET) is an...

Cerebral glucose metabolic decline (left angular gyrus)

586

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-09

Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype.

Kim BH, Choi YH et al.

J Alzheimers Dis

Alzheimer's disease (AD) is a common neurodegenerative disorder characterized by a heterogeneous dis...

Cortical thickness

919

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-20

Genome-Wide Association Study Identifies SLAMF1 Affecting the Rate of Memory Decline.

Chen SD, Li HQ et al.

J Alzheimers Dis

As cognitive function declines with age, identifying factors affecting the trajectory of cognitive d...

Memory decline

709

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-23

Effects of Multiple Genetic Loci on Age at Onset in Frontotemporal Dementia.

Ferrari R, Grassi M et al.

J Alzheimers Dis

In frontotemporal dementia (FTD), age at disease onset (AAO) is unpredictable in both early and late...

Frontotemporal dementia (age at onset)

411

Participants

N/A

Studies

Details PubMed

GWAS 2015-10-30

Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians.

Kim S, Nho K et al.

J Alzheimers Dis

Plasma homocysteine, a metabolite involved in key cellular methylation processes seems to be implica...

Plasma homocysteine levels

1858

Participants

N/A

Studies

Details PubMed

GWAS 2015-02-03

Genetic Determinants of Survival in Patientswith Alzheimer’s Disease.

Wang X, Lopez O et al.

J Alzheimers Dis

There is a strong genetic basis for late-onset of Alzheimer’s disease (LOAD), and thus far >20 ge...

Alzheimer's disease (survival time)

983

Participants

N/A

Studies

Details PubMed

GWAS 2012-07-11

Identification of a late onset Alzheimer's disease candidate risk variant at 9q21.33 in Polish patients.

Gaj P, Paziewska A et al.

J Alzheimers Dis

Late onset Alzheimer's disease (LOAD) accounts for about 95% of all Alzheimer's disease cases. While...

Alzheimer's disease

282

Participants

N/A

Studies

Details PubMed

GWAS 2010-11-25

Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data.

Sherva R, Baldwin CT et al.

J Alzheimers Dis

Alzheimer's disease (AD) is highly prevalent in Wadi Ara despite the low frequency of apolipoprotein...

Alzheimer's disease

Replicated

5543

Participants

N/A

Studies

Details PubMed

GWAS 2009-09-11

Genome-wide scan of copy number variation in late-onset Alzheimer's disease.

Heinzen EL, Need AC et al.

J Alzheimers Dis

Alzheimer's disease is a complex and progressive neurodegenerative disease leading to loss of memory...

Alzheimer's disease

699

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.

Dai Y, Hsu YC et al.

J Alzheimers Dis

Accelerated cognitive decline

2024-01-31

Genome-Wide Association Study of Incident Dementia in a Community-Based Sample of Older Subjects.

Harper JD, Fan KH et al.

J Alzheimers Dis

Alzheimer's disease

2022-06-09

Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study.

Kang S, Gim J et al.

J Alzheimers Dis

Late-onset Alzheimer's disease

2021-06-18

Genome-Wide Association Study of Brain Alzheimer's Disease-Related Metabolic Decline as Measured by [18F] FDG-PET Imaging.

Wang RZ, Yang YX et al.

J Alzheimers Dis

Cerebral glucose metabolic decline (left angular gyrus)

2020-08-10

Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype.

Kim BH, Choi YH et al.

J Alzheimers Dis

Cortical thickness

2020-04-09

Genome-Wide Association Study Identifies SLAMF1 Affecting the Rate of Memory Decline.

Chen SD, Li HQ et al.

J Alzheimers Dis

Memory decline

2020-01-20

Effects of Multiple Genetic Loci on Age at Onset in Frontotemporal Dementia.

Ferrari R, Grassi M et al.

J Alzheimers Dis

Frontotemporal dementia (age at onset)

2017-01-23

Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians.

Kim S, Nho K et al.

J Alzheimers Dis

Plasma homocysteine levels

2015-10-30

Genetic Determinants of Survival in Patientswith Alzheimer’s Disease.

Wang X, Lopez O et al.

J Alzheimers Dis

Alzheimer's disease (survival time)

2015-02-03

Identification of a late onset Alzheimer's disease candidate risk variant at 9q21.33 in Polish patients.

Gaj P, Paziewska A et al.

J Alzheimers Dis

Alzheimer's disease

2012-07-11

Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data.

Sherva R, Baldwin CT et al.

J Alzheimers Dis

Alzheimer's disease

2010-11-25

Genome-wide scan of copy number variation in late-onset Alzheimer's disease.

Heinzen EL, Need AC et al.

J Alzheimers Dis

Alzheimer's disease

2009-09-11