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GWAS 2022-10-12

Whole-genome sequencing unravels novel genetic determinants and regulatory pathways associated with triamcinolone acetonide-induced ocular hypertension.

Badrinarayanan L, Nagarajan H et al.

Mol Genet Genomics

Glucocorticosteroids commonly used to treat certain ocular inflammatory conditions cause an unwarran...

Triamcinolone acetonide-induced ocular hypertension

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-02

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE.

Zhang YM, Zhou XJ et al.

Mol Genet Genomics

An autoimmune component has been suggested to play a role in pathogenesis of IgA nephropathy (IgAN)....

IgA nephropathy

2079

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-24

Three pleiotropic loci associated with bone mineral density and lean body mass.

Zhang YX, Zhang SS et al.

Mol Genet Genomics

Both bone mineral density (BMD) and lean body mass (LBM) are important physiological measures with s...

Bone mineral density or leg lean mass (pleiotropy)

Replicated

512445

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-04

Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians.

Giri AK, Prasad G et al.

Mol Genet Genomics

Obesity, a risk factor for multiple diseases (e.g. diabetes, hypertension, cancers) originates throu...

Body mass index

Replicated

7259

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-07

Additional common loci associated with stroke and obesity identified using pleiotropic analytical approach.

Wang L, Xu F et al.

Mol Genet Genomics

Stroke is a complex disease with multiple etiologies. Numerous studies suggest an established associ...

Stroke and BMI (pleiotropy)

1127971

Participants

N/A

Studies

Details PubMed

GWAS 2018-01-11

Identifying potentially common genes between dyslipidemia and osteoporosis using novel analytical approaches.

Lin X, Peng C et al.

Mol Genet Genomics

Dyslipidemia (DL) is closely related to osteoporosis (OP), while the exact common genetic mechanisms...

Femoral neck bone mineral density or plasma lipids (pleiotropy)

238565

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-09

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

Yasukochi Y, Sakuma J et al.

Mol Genet Genomics

Chronic kidney disease and hyperuricemia are serious global health problems. Recent genome-wide asso...

Chronic kidney disease

Replicated

5048

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole-genome sequencing unravels novel genetic determinants and regulatory pathways associated with triamcinolone acetonide-induced ocular hypertension.

Badrinarayanan L, Nagarajan H et al.

Mol Genet Genomics

Triamcinolone acetonide-induced ocular hypertension

2022-10-12

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE.

Zhang YM, Zhou XJ et al.

Mol Genet Genomics

IgA nephropathy

2021-06-02

Three pleiotropic loci associated with bone mineral density and lean body mass.

Zhang YX, Zhang SS et al.

Mol Genet Genomics

Bone mineral density or leg lean mass (pleiotropy)

2020-09-24

Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians.

Giri AK, Prasad G et al.

Mol Genet Genomics

Body mass index

2020-05-04

Additional common loci associated with stroke and obesity identified using pleiotropic analytical approach.

Wang L, Xu F et al.

Mol Genet Genomics

Stroke and BMI (pleiotropy)

2019-12-07

Identifying potentially common genes between dyslipidemia and osteoporosis using novel analytical approaches.

Lin X, Peng C et al.

Mol Genet Genomics

Femoral neck bone mineral density or plasma lipids (pleiotropy)

2018-01-11

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

Yasukochi Y, Sakuma J et al.

Mol Genet Genomics

Chronic kidney disease

2017-11-09