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GWAS 2025-03-06

A genome-wide association study identifies a novel East Asian-specific locus for dementia with Lewy bodies in Japanese subjects.

Mitsumori R, Asanomi Y et al.

Mol Med

Dementia with Lewy bodies (DLB) is the second most common type of degenerative dementia in older pat...

Dementia with Lewy bodies

6324

Participants

N/A

Studies

Details PubMed

GWAS 2018-06-11

Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study.

Chattopadhyay S, Thomsen H et al.

Mol Med

Recent identification of 10 germline variants predisposing to monoclonal gammopathy of undetermined ...

Monoclonal gammopathy of undetermined significance

1528

Participants

N/A

Studies

Details PubMed

GWAS 2018-04-11

Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level.

Matana A, Brdar D et al.

Mol Med

Parathyroid hormone (PTH) is one of the principal regulators of calcium homeostasis. Although serum ...

Plasma parathyroid hormone levels

2596

Participants

N/A

Studies

Details PubMed

GWAS 2017-08-31

Efficient genome-wide association in biobanks using topic modeling identifies multiple novel disease loci.

McCoy TH, Castro VM et al.

Mol Med

Biobanks and national registries represent a powerful tool for genomic discovery, but rely on diagno...

Disease topic 00

10845

Participants

N/A

Studies

Details PubMed

GWAS 2015-10-10

Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations.

Seldin MF, Alkhairy OK et al.

Mol Med

To investigate the genetics of late-onset myasthenia gravis (LOMG), we conducted a genome-wide assoc...

Late-onset myasthenia gravis

2660

Participants

N/A

Studies

Details PubMed

GWAS 2014-08-14

Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans.

Govind N, Choudhury A et al.

Mol Med

The aim of this study was to identify genetic variants associated with rheumatoid arthritis (RA) ris...

Rheumatoid arthritis

637

Participants

N/A

Studies

Details PubMed

GWAS 2010-08-24

Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement.

Uhl GR, Drgon T et al.

Mol Med

Abilities to successfully quit smoking display substantial evidence for heritability in classic and ...

Smoking cessation

369

Participants

N/A

Studies

Details PubMed

GWAS 2009-03-14

Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis.

Cui J, Taylor KE et al.

Mol Med

We carried out a genome-wide association study of genetic predictors of anti-cyclic citrullinated pe...

Anti-cyclic Citrullinated Peptide Antibody

Replicated

1380

Participants

N/A

Studies

Details PubMed

GWAS 2008-11-09

Genome-wide association for nicotine dependence and smoking cessation success in NIH research volunteers.

Drgon T, Montoya I et al.

Mol Med

Phenotypes related to both nicotine dependence and ability to successfully quit smoking display subs...

Nicotine dependence

480

Participants

N/A

Studies

Details PubMed

GWAS 2008-07-10

Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.

Liu C, Batliwalla F et al.

Mol Med

The prediction of response (or non-response) to anti-TNF treatment for rheumatoid arthritis (RA) is ...

Response to TNF antagonist treatment

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study identifies a novel East Asian-specific locus for dementia with Lewy bodies in Japanese subjects.

Mitsumori R, Asanomi Y et al.

Mol Med

Dementia with Lewy bodies

2025-03-06

Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study.

Chattopadhyay S, Thomsen H et al.

Mol Med

Monoclonal gammopathy of undetermined significance

2018-06-11

Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level.

Matana A, Brdar D et al.

Mol Med

Plasma parathyroid hormone levels

2018-04-11

Efficient genome-wide association in biobanks using topic modeling identifies multiple novel disease loci.

McCoy TH, Castro VM et al.

Mol Med

Disease topic 00

2017-08-31

Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations.

Seldin MF, Alkhairy OK et al.

Mol Med

Late-onset myasthenia gravis

2015-10-10

Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans.

Govind N, Choudhury A et al.

Mol Med

Rheumatoid arthritis

2014-08-14

Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement.

Uhl GR, Drgon T et al.

Mol Med

Smoking cessation

2010-08-24

Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis.

Cui J, Taylor KE et al.

Mol Med

Anti-cyclic Citrullinated Peptide Antibody

2009-03-14

Genome-wide association for nicotine dependence and smoking cessation success in NIH research volunteers.

Drgon T, Montoya I et al.

Mol Med

Nicotine dependence

2008-11-09

Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.

Liu C, Batliwalla F et al.

Mol Med

Response to TNF antagonist treatment

2008-07-10