Active: Thromb Haemost Clear all

GWAS 2022-03-10

Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk.

Lopez S, Martinez-Perez A et al.

Thromb Haemost

Plasma cell-free DNA (cfDNA) is a surrogate marker of neutrophil extracellular traps (NETs) that con...

Circulating cell-free DNA

935

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-16

Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism.

Herrera-Rivero M, Stoll M et al.

Thromb Haemost

Previous genome-wide association studies (GWASs) have established several susceptibility genes for v...

Venous thromboembolism

1863

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-19

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans.

Tunjungputri RN, Li Y et al.

Thromb Haemost

Inflammation and coagulation are key processes in cardiovascular diseases (CVDs). The Canakinumab An...

Platelet count and reactivity phenotypes

534

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-13

Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery.

Karhausen JA, Qi W et al.

Thromb Haemost

Introduction: Thrombocytopenia after cardiac surgery independently predicts stroke, acute kidney inj...

Thrombocytopenia in coronary artery bypass surgery

Replicated

608

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-01

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.

Stanne TM, Olsson M et al.

Thromb Haemost

Thrombin-activatable fibrinolysis inhibitor (TAFI) plays a central role in haemostasis, and plasma T...

Thrombin-activatable fibrinolysis inhibitor levels

3116

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-16

Identification of unique venous thromboembolism-susceptibility variants in African-Americans.

Heit JA, Armasu SM et al.

Thromb Haemost

To identify novel single nucleotide polymorphisms (SNPs) associated with venous thromboembolism (VTE...

Venous thromboembolism adjusted for sickle cell variant rs77121243-T

5334

Participants

N/A

Studies

Details PubMed

GWAS 2016-09-22

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

Zhang W, Jernerén F et al.

Thromb Haemost

L-arginine is the essential precursor of nitric oxide, and is involved in multiple key physiological...

L-arginine levels

Replicated

6276

Participants

N/A

Studies

Details PubMed

GWAS 2016-04-21

Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression.

Müller-Calleja N, Rossmann H et al.

Thromb Haemost

The antiphospholipid syndrome (APS) is characterised by venous and/or arterial thrombosis and pregna...

Presence of antiphospholipid antibodies

4163

Participants

N/A

Studies

Details PubMed

GWAS 2014-12-11

A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record.

Karnes JH, Cronin RM et al.

Thromb Haemost

Heparin-induced thrombocytopenia (HIT) is an unpredictable, potentially catastrophic adverse effect ...

Heparin-induced thrombocytopenia

Replicated

1376

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk.

Lopez S, Martinez-Perez A et al.

Thromb Haemost

Circulating cell-free DNA

2022-03-10

Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism.

Herrera-Rivero M, Stoll M et al.

Thromb Haemost

Venous thromboembolism

2021-02-16

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans.

Tunjungputri RN, Li Y et al.

Thromb Haemost

Platelet count and reactivity phenotypes

2018-11-19

Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery.

Karhausen JA, Qi W et al.

Thromb Haemost

Thrombocytopenia in coronary artery bypass surgery

2018-08-13

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.

Stanne TM, Olsson M et al.

Thromb Haemost

Thrombin-activatable fibrinolysis inhibitor levels

2018-02-01

Identification of unique venous thromboembolism-susceptibility variants in African-Americans.

Heit JA, Armasu SM et al.

Thromb Haemost

Venous thromboembolism adjusted for sickle cell variant rs77121243-T

2017-02-16

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

Zhang W, Jernerén F et al.

Thromb Haemost

L-arginine levels

2016-09-22

Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression.

Müller-Calleja N, Rossmann H et al.

Thromb Haemost

Presence of antiphospholipid antibodies

2016-04-21

A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record.

Karnes JH, Cronin RM et al.

Thromb Haemost

Heparin-induced thrombocytopenia

2014-12-11