Active: Transl Psychiatry Clear all

GWAS 2025-06-20

Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.

Bentley AR, Brown MR et al.

Transl Psychiatry

Serum lipid levels, which are influenced by both genetic and environmental factors, are key determin...

HDL x anxiety interaction (1df test)

19133

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-23

Shared genetic architecture and causality between autism spectrum disorder and irritable bowel syndrome, multisite pain, and fatigue.

Li Y, Xie T et al.

Transl Psychiatry

Autism spectrum disorder (ASD) often co-occurs with functional somatic syndromes (FSS), such as irri...

Autism spectrum disorder (MTAG)

46350

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-27

Nightmares share genetic risk factors with sleep and psychiatric traits.

Ollila HM, Sinnott-Armstrong N et al.

Transl Psychiatry

Nightmares are vivid, extended, and emotionally negative or negative dreams that awaken the dreamer....

Nightmare

45255

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-13

Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.

Nuñez NA, Coombes BJ et al.

Transl Psychiatry

There is increasing interest in individualizing treatment selection for more than 25 regulatory appr...

Antidepressant-associated treatment emergent mania in BD

861

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-06

Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population.

Park K, Do AR et al.

Transl Psychiatry

Although depression is an emerging disorder affecting many people worldwide, most genetic studies ha...

Depressive symptoms

Replicated

10138

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-29

Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.

Shigemizu D, Akiyama S et al.

Transl Psychiatry

Late-onset Alzheimer's disease (LOAD) is the most common multifactorial neurodegenerative disease am...

Late-onset Alzheimer's disease

4139

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-26

The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders.

Ou YN, Ge YJ et al.

Transl Psychiatry

The fornix is a white matter bundle located in the center of the hippocampaldiencephalic limbic circ...

Fornix white matter microstructure (fractional anisotropy)

Replicated

34445

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-29

Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment.

Granot-Hershkovitz E, Spitzer B et al.

Transl Psychiatry

We studied the genetic associations of a previously developed Metabolomic Risk Score (MRS) for Mild ...

Metabolomic risk score for mild cognitive impairment

Replicated

11846

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-31

Visual masking deficits in schizophrenia: a view into the genetics of the disease through an endophenotype.

Shaqiri A, Hodel F et al.

Transl Psychiatry

Schizophrenia is a severe psychiatric disorder determined by a complex mixture of genetic and enviro...

Visual backward masking performance (SOA25)

458

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-15

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.

Strom NI, Smit DJA et al.

Transl Psychiatry

Hoarding Disorder (HD) is a mental disorder characterized by persistent difficulties discarding or p...

Hoarding symptoms

27537

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-30

Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants.

Sun J, Wang W et al.

Transl Psychiatry

To date, little is known about the pleiotropic genetic variants among depression, cognition, and mem...

Depression, cognition and memory (multivariate analysis)

Replicated

2408

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-25

The interaction of early life factors and depression-associated loci affecting the age at onset of the depression.

Chen Y, Pan C et al.

Transl Psychiatry

Multiple previous studies explored the associations between early life factors and the age at onset ...

Age of onset of depression x felt loved as a child interaction

35633

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.

Bentley AR, Brown MR et al.

Transl Psychiatry

HDL x anxiety interaction (1df test)

2025-06-20

Shared genetic architecture and causality between autism spectrum disorder and irritable bowel syndrome, multisite pain, and fatigue.

Li Y, Xie T et al.

Transl Psychiatry

Autism spectrum disorder (MTAG)

2024-11-23

Nightmares share genetic risk factors with sleep and psychiatric traits.

Ollila HM, Sinnott-Armstrong N et al.

Transl Psychiatry

Nightmare

2024-02-27

Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.

Nuñez NA, Coombes BJ et al.

Transl Psychiatry

Antidepressant-associated treatment emergent mania in BD

2024-02-13

Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population.

Park K, Do AR et al.

Transl Psychiatry

Depressive symptoms

2024-02-06

Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.

Shigemizu D, Akiyama S et al.

Transl Psychiatry

Late-onset Alzheimer's disease

2023-06-29

The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders.

Ou YN, Ge YJ et al.

Transl Psychiatry

Fornix white matter microstructure (fractional anisotropy)

2023-05-26

Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment.

Granot-Hershkovitz E, Spitzer B et al.

Transl Psychiatry

Metabolomic risk score for mild cognitive impairment

2023-04-29

Visual masking deficits in schizophrenia: a view into the genetics of the disease through an endophenotype.

Shaqiri A, Hodel F et al.

Transl Psychiatry

Visual backward masking performance (SOA25)

2022-12-31

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.

Strom NI, Smit DJA et al.

Transl Psychiatry

Hoarding symptoms

2022-11-15

Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants.

Sun J, Wang W et al.

Transl Psychiatry

Depression, cognition and memory (multivariate analysis)

2022-07-30

The interaction of early life factors and depression-associated loci affecting the age at onset of the depression.

Chen Y, Pan C et al.

Transl Psychiatry

Age of onset of depression x felt loved as a child interaction

2022-07-25