A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.
Ising M, Lucae S, Binder EB et al.
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Abstract
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Context: The efficacy of antidepressant drug treatment in depression is unsatisfactory; 1 in 3 patients does not fully recover even after several treatment trials. Genetic factors and clinical characteristics contribute to the failure of a favorable treatment outcome.
700 European ancestry cases
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