Genome-wide association scan of Dupuytren's disease.
Ojwang JO, Adrianto I, Gray-McGuire C et al.
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Abstract
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Purpose: Dupuytren's disease (DD) has a strong genetic component that is suggested by population studies and family clustering. Genetic studies have yet to identify the gene(s) involved in DD. The purpose of this study was to identify regions of the entire genome (chromosomes 1-23) associated with the disease by performing a genome-wide association scan on DD patients and controls.
37 European ancestry cases, 36 European ancestry controls
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