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GWAS Study

Genome-wide association study of motor coordination problems in ADHD identifies genes for brain and muscle function.

Fliers EA, Vasquez AA, Poelmans G et al.

21473668 PubMed ID
GWAS Study Type
1186 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FE
Fliers EA
VA
Vasquez AA
PG
Poelmans G
RN
Rommelse N
AM
Altink M
BC
Buschgens C
AP
Asherson P
BT
Banaschewski T
ER
Ebstein R
GM
Gill M
MA
Miranda A
MF
Mulas F
OR
Oades RD
RH
Roeyers H
RA
Rothenberger A
SJ
Sergeant J
SE
Sonuga-Barke E
SH
Steinhausen HC
FS
Faraone SV
BJ
Buitelaar JK
FB
Franke B
Chapter II

Abstract

Summary of the research findings

Objectives: Motor coordination problems are frequent in children with attention deficit/hyperactivity disorder (ADHD). We performed a genome-wide association study to identify genes contributing to motor coordination problems, hypothesizing that the presence of such problems in children with ADHD may identify a sample of reduced genetic heterogeneity.

890 European ancestry children

Chapter III

Study Statistics

Key metrics and study information

1186
Total Participants
GWAS
Study Type
Yes
Replicated
296 European ancestry children
Replication Participants
European
Ancestry
Israel, Iceland, Netherlands, Belgium, Germany, U.K., Switzerland, Spain
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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