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GWAS Study

Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass.

Sun L, Tan LJ, Lei SF et al.

22087292 PubMed ID
GWAS Study Type
3913 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SL
Sun L
TL
Tan LJ
LS
Lei SF
CX
Chen XD
LX
Li X
PR
Pan R
YF
Yin F
LQ
Liu QW
YX
Yan XF
PC
Papasian CJ
DH
Deng HW
Chapter II

Abstract

Summary of the research findings

Objective: Femoral neck geometric parameters (FNGPs), such as periosteal diameter (W), cross-sectional area (CSA), cortical thickness (CT), buckling ratio (BR), and section modulus (Z), are highly genetically correlated with body lean mass. However, the specific SNPs/genes shared by these phenotypes are largely unknown.

1,627 Han Chinese ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

3913
Total Participants
GWAS
Study Type
Yes
Replicated
2,286 European ancestry individuals
Replication Participants
East Asian, European
Ancestry
China, U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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