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GWAS Study

Identification of six loci associated with pelvic organ prolapse using genome-wide association analysis.

Allen-Brady K, Cannon-Albright L, Farnham JM et al.

22105264 PubMed ID
GWAS Study Type
3167 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AK
Allen-Brady K
CL
Cannon-Albright L
FJ
Farnham JM
TC
Teerlink C
VM
Vierhout ME
VK
van Kempen LCL
KK
Kluivers KB
NP
Norton PA
Chapter II

Abstract

Summary of the research findings

Objective: There is evidence that both environmental and genetic factors contribute to pelvic organ prolapse. We conducted a genome-wide association study to investigate whether common genetic variants modify the risk of pelvic organ prolapse.

115 European ancestry cases, 2,976 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3167
Total Participants
GWAS
Study Type
Yes
Replicated
76 European ancestry cases
Replication Participants
European
Ancestry
U.S., Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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