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GWAS Study

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

O'Donnell CJ, Kavousi M, Smith AV et al.

22144573 PubMed ID
GWAS Study Type
15993 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

OC
O'Donnell CJ
KM
Kavousi M
SA
Smith AV
KS
Kardia SL
FM
Feitosa MF
HS
Hwang SJ
SY
Sun YV
PM
Province MA
AT
Aspelund T
DA
Dehghan A
HU
Hoffmann U
BL
Bielak LF
ZQ
Zhang Q
EG
Eiriksdottir G
VD
van Duijn CM
FC
Fox CS
DA
de Andrade M
KA
Kraja AT
SS
Sigurdsson S
ES
Elias-Smale SE
MJ
Murabito JM
LL
Launer LJ
VD
van der Lugt A
KS
Kathiresan S
KG
Krestin GP
HD
Herrington DM
HT
Howard TD
LY
Liu Y
PW
Post W
MB
Mitchell BD
OJ
O'Connell JR
SH
Shen H
SA
Shuldiner AR
AD
Altshuler D
ER
Elosua R
SV
Salomaa V
SS
Schwartz SM
SD
Siscovick DS
VB
Voight BF
BJ
Bis JC
GN
Glazer NL
PB
Psaty BM
BE
Boerwinkle E
HG
Heiss G
BS
Blankenberg S
ZT
Zeller T
WP
Wild PS
SR
Schnabel RB
SA
Schillert A
ZA
Ziegler A
MT
Münzel TF
WC
White CC
RJ
Rotter JI
NM
Nalls M
OM
Oudkerk M
JA
Johnson AD
NA
Newman AB
UA
Uitterlinden AG
MJ
Massaro JM
CJ
Cunningham J
HT
Harris TB
HA
Hofman A
PP
Peyser PA
BI
Borecki IB
CL
Cupples LA
GV
Gudnason V
WJ
Witteman JC
Chapter II

Abstract

Summary of the research findings

Coronary artery calcification (CAC) detected by computed tomography is a noninvasive measure of coronary atherosclerosis, which underlies most cases of myocardial infarction (MI). We sought to identify common genetic variants associated with CAC and further investigate their associations with MI.

9,961 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

15993
Total Participants
GWAS
Study Type
Yes
Replicated
6,032 European ancestry individuals
Replication Participants
European
Ancestry
U.S., Iceland, Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.